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Poliomyelitis (/ ˌ p oʊ l i oʊ ˌ m aɪ ə ˈ l aɪ t ɪ s / POH-lee-oh-MY-ə-LY-tiss), commonly shortened to polio, is an infectious disease caused by the poliovirus. [1] Approximately 75% of cases are asymptomatic; [5] mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia.
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
The polio vaccine has all but obliterated the illness that once killed thousands and paralyzed 15,000 people nationwide every year. ... which is why it sometimes triggers spinal and respiratory ...
Furthermore, the attack rate on this group was 1.6%. Two-year-olds had the highest attack rate per 100,000 people at 1.84%. [4] Additionally, the death rate was very high, particularly for the younger age groups. At the height of the epidemic, which was from June 1 to November 1, the death rate from polio in the greater New York City area was ...
In the early 1950s, before Salk’s vaccine, polio outbreaks caused more than 15,000 cases of paralysis each year, the CDC said. After the vaccines — there are two: trivalent inactivated ...
With a single case of paralytic polio detected in Rockland County, New York, and the virus showing up in wastewater samples in two counties in the state, as well as New York City, health officials ...
Numerous observational studies and randomised trials (RCTs) have found that the impact on mortality of live and inactivated vaccines differ markedly. All live vaccines studied so far (BCG, measles vaccine, oral polio vaccine (OPV) and smallpox vaccine) have been shown to reduce mortality more than can be explained by prevention of the targeted infection(s).
In the control group, Brodie reported that five out of 4500 developed polio; in the group receiving the vaccine, one out of 7,000 developed polio. This difference is not quite statistically significant, and other researchers believed that the one case was likely caused by the vaccine. Two more possible cases were reported later. [11]