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Diethylcarbamazine is a medication used in the treatment of filariasis including lymphatic filariasis, tropical pulmonary eosinophilia, and loiasis. [1] It may also be used for prevention of loiasis in those at high risk. [1] While it has been used for onchocerciasis (river blindness), ivermectin is preferred. [2] It is taken by mouth. [3]
The recommended treatment for people outside the United States is albendazole combined with ivermectin. [13] [14] A combination of diethylcarbamazine and albendazole is also effective. [13] [15] Side effects of the drugs include nausea, vomiting, and headaches. [16] All of these treatments are microfilaricides; they have no effect on the adult ...
Lymphatic filariasis is a human disease caused by parasitic worms known as filarial worms. [2] [3] Usually acquired in childhood, it is a leading cause of permanent disability worldwide, impacting over a hundred million people and manifesting itself in a variety of severe clinical pathologies [6] [7] While most cases have no symptoms, some people develop a syndrome called elephantiasis, which ...
Lymphatic filariasis, also known as elephantiasis, is a condition characterized by swelling of the lower limbs. The two other filarial causes of lymphatic filariasis are Wuchereria bancrofti and Brugia timori, which both differ from B. malayi morphologically, symptomatically, and in geographical extent. [1]
The prevention and treatment plans differ according to whatever is effective against the species in a given region. [2] The creation of maps and planning of local monitoring systems has been an essential part of all regional eradication plans. [3]
Where the diseases are endemic many times more are exposed routinely to infection. Some victims harbour more than one medically significant infection simultaneously and this can complicate diagnosis and treatment. [7] Humankind is the definitive host of at least eight species of filariae in various families. Six are particularly significant in ...
Lymphatic filariasis in India refers to the presence of the disease lymphatic filariasis in India and the social response to the disease. In India, 99% of infections come from a type of mosquito spreading a type of worm through a mosquito bite. [1] The treatment plan provides 400 million people in India with medication to eliminate the parasite ...
Treatment of loiasis involves chemotherapy or, in some cases, surgical removal of adult worms followed by systemic treatment. The current drug of choice for therapy is diethylcarbamazine (DEC), with the recommended dosage of DEC for adults and pediatrics being 8–10 mg/kg/d taken three times daily for 21 days per the CDC.