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Prednisolone has a relatively short half-life, ranging 2–4 hours. It also has a large therapeutic window, considering the dosage required to produce a therapeutic effect is a few times higher than what the body naturally produces. [14] Prednisolone is 70–90% plasma protein bound, it binds to proteins such as albumin. [14]
Croup affects about 15% of children, and usually presents between the ages of 6 months and 5–6 years. [ 4 ] [ 5 ] It accounts for about 5% of hospital admissions in this population. [ 3 ] In rare cases, it may occur in children as young as 3 months and as old as 15 years. [ 3 ]
The WHO Model List of Essential Medicines for Children (aka Essential Medicines List for Children [1] or EMLc [1]), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe in children up to twelve years of age to meet the most important needs in a health system.
Methylprednisolone dose and duration have been implicated in PAE development. 20 mg/day of prednisone (16 mg/day of methylprednisolone) is the threshold dosage for PAE development agreed upon by many studies. [24]
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The procedure is to take the child's weight in pounds, divide by 150 lb, and multiply the fractional result by the adult dose to find the equivalent child dosage.For example, if an adult dose of medication calls for 30 mg and the child weighs 30 lb, divide the weight by 150 (30/150) to obtain 1/5 and multiply 1/5 times 30 mg to get 6 mg.
“Do you guys know what they pay us?” Davidson said. “It’s like $3,000 an episode. I got dinner.” At first, it sounded like a lot of money.
Prednisolone sodium phosphate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. References. External links "Prednisolone sodium phosphate ...
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