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The melanocyte-stimulating hormones, known collectively as MSH, also known as melanotropins or intermedins, are a family of peptide hormones and neuropeptides consisting of α-melanocyte-stimulating hormone (α-MSH), β-melanocyte-stimulating hormone (β-MSH), and γ-melanocyte-stimulating hormone (γ-MSH) that are produced by cells in the pars intermedia of the anterior lobe of the pituitary ...
α-Melanocyte-stimulating hormone (α-MSH) is an endogenous peptide hormone and neuropeptide of the melanocortin family, with a tridecapeptide structure and the amino acid sequence Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH 2.
The melanocortin 1 receptor (MC1R), also known as melanocyte-stimulating hormone receptor (MSHR), melanin-activating peptide receptor, or melanotropin receptor, is a G protein–coupled receptor that binds to a class of pituitary peptide hormones known as the melanocortins, which include adrenocorticotropic hormone (ACTH) and the different forms of melanocyte-stimulating hormone (MSH).
β-Melanocyte-stimulating hormone (β-MSH) is an endogenous peptide hormone and neuropeptide. [1] It is a melanocortin, specifically, one of the three types of melanocyte-stimulating hormone (MSH), and is produced from proopiomelanocortin (POMC). [1] It is an agonist of the MC 1, MC 3, MC 4, and MC 5 receptors. [1] It contains 23 amino acid ...
After a short period of time, ACTH is cleaved into α-melanocyte-stimulating hormone (α-MSH) and CLIP, a peptide with unknown activity in humans. In human body, total weight ACTH is 4,540 atomic mass units (Da). [9]
As Susan Boulware, associate professor of clinical pediatrics and medical director for Yale School of Medicine's Gender Program, tells Yahoo Life, hormone therapy is a broad term used to describe ...
γ-Melanocyte-stimulating hormone (γ-MSH) is an endogenous peptide hormone and neuropeptide. [1] It is a melanocortin, specifically, one of the three types of melanocyte-stimulating hormone (MSH), and is produced from proopiomelanocortin (POMC). [1] It is an agonist of the MC 1, MC 3, MC 4, and MC 5 receptors. [1]
Lerner is perhaps best known for leading the team of researchers who isolated and named, in 1958, the hormone melatonin. He was an expert in the metabolic basis of inherited diseases, particularly vitiligo for which he, in the 1980s, developed a skin transplantation therapy. Lerner also isolated the compound melanocyte-stimulating hormone (MSH ...