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The FDA just approved elagolix, a new treatment for women living with endometriosis. An estimated 4 to 10 million women in the US are living with endometriosis, a condition in which tissue from ...
A new clinical trial has been launched after previous studies showed promise. Scientists hunt for potential first new endometriosis drug in 40 years Skip to main content
The researchers also showed that 4-hydroxyindole reduced endometriosis initiation and progression in animal models, so suggest that it might be an effective treatment for the condition ...
[9] [36] It was the first new medication to be approved by the FDA for the treatment of endometriosis in more than a decade. [37] [38] Elagolix was the first member of a new class of GnRH modulators described as "second-generation" due to their non-peptide and small-molecule nature and oral activity to be marketed.
Endometriosis can lead to ovarian cysts (endometriomas), adhesions, and damage to the fallopian tubes or ovaries, all of which can interfere with ovulation and fertilization. Treatment for endometriosis often includes hormonal therapies, pain management, and in some cases, surgery to remove the endometrial tissue.
Elagolix – gonadotropin-releasing hormone receptor antagonist undergoing FDA review for the treatment of endometriosis and in clinical trials for uterine fibroids [6] Opicapone – A once daily catechol-O-methyl transferase inhibitor in trials for Parkinson's disease [5] NBI-74788 – Corticotropin-releasing factor (CRF) receptor agonist [36]
Research to find better treatments is ongoing. Funding for endometriosis research doubled in 2021. This is amazing, since the condition is a problem for so many women and girls.
The condition impacts up to 10% of reproductive-age women and has very few effective treatments. [ 2 ] [ 4 ] She has studied the genetic factors that underpin risk to endometriosis, and uses this work to design new therapeutic treatments.