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1α-Hydroxyvitamin D 5 is a chemical derivative of vitamin D 5.The motive to study 1α-hydroxyvitamin D 5 as a potential pharmaceutical drug stemmed from the tendency of calcitriol, a natural metabolite produced in the kidney, to cause toxic hypercalcemia in patients when dosed at concentrations needed to interrupt prostate cancer cells' cycle and stimulate apoptosis.
The liver is required to transform vitamin D into 25-hydroxyvitamin D. This is an inactive metabolite of vitamin D but is a necessary precursor (building block) to create the active form of vitamin D. [1] The kidneys are responsible for converting 25-hydroxyvitamin D to 1,25-hydroxyvitamin D. This is the active form of vitamin D in the body.
For all people over the age of 1, including women who are pregnant or lactating, they set an adequate intake of 15 μg/day (600 IU). [58] On the other hand, the EU Commission defined nutrition labelling for foodstuffs as regards recommended daily allowances (RDA) for vitamin D to 5 μg/day (200 IU) as 100%. [174]
Most over-the-counter vitamin D supplements are between 1,000 and 5,000 IU, and some are as high as 10,000 IU, says Adamian. "There's so many different supplements, so it's very important to ...
While men are less likely to develop osteoporosis, it is possible and has been occurring more often in recent years in men over age 65. “Most men should aim for 1,000 - 1,200mg of calcium per ...
The European Food Safety Authority recommends 2.0 litres (70 imp fl oz; 68 US fl oz) of total water per day for women and 2.5 litres (88 imp fl oz; 85 US fl oz) per day for men. [ 3 ] The common advice to drink 8 glasses (1,900 mL or 64 US fl oz) of plain water per day is not scientific; thirst is a better guide for how much water to drink than ...
The average person age 65 and older has $272,588 in his or her 401(k), according to the latest data from retirement giant Vanguard. While the average 401(k) participant has $272,588, the median ...
A reference range is usually defined as the set of values 95 percent of the normal population falls within ... 65, [24] 76 [15] ... Higher in pregnant women [172] 0.5 ...
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