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  2. Memantine - Wikipedia

    en.wikipedia.org/wiki/Memantine

    Memantine has a relatively high volume of distribution (V d) of 9 to 11 L/kg. [8] [9] It easily crosses biological membranes, is widely distributed throughout the body, and crosses the blood–brain barrier into the central nervous system. [9] The drug is transported across the blood–brain barrier by the organic cation transporter novel 1 ...

  3. Evergreening - Wikipedia

    en.wikipedia.org/wiki/Evergreening

    In one case, product hopping of the multiple sclerosis drug glatiramer acetate (Copaxone) led to a cost to consumers of $4.3 to 6.5 billion dollars over two and a half years, before the new patent was invalidated by the courts. [13] Another example was the Alzheimer's drug memantine (Namenda). [12]

  4. The 10 Biggest-Selling Drugs That Are About to Lose Their Patent

    www.aol.com/news/2011-02-27-top-selling-drugs...

    In 2006, generic drugmaker Apotex briefly marketed generic Plavix, but was ordered to stop until November 2011. The order was extended recently by the FDA, but Plavix's patent is set to expire on ...

  5. Forest Laboratories - Wikipedia

    en.wikipedia.org/wiki/Forest_Laboratories

    The other drug-related charge was a misdemeanor charge of distributing the unapproved drug Levothroid in violation of the Federal Food, Drug, and Cosmetic Act. Certain of the criminal activities were revealed with the help of whistleblowers, who received $14 million from the settlement. [11] [12] [13]

  6. GlaxoSmithKline, Sanofi-Aventis: Rx for When Drug Patents Expire

    www.aol.com/news/2010-03-31-glaxosmithkline...

    GlaxoSmithKline, Sanofi-Aventis: Rx for When Drug Patents Expire. Melly Alazraki. Updated July 14, 2016 at 6:02 PM. drugmakers.

  7. List of withdrawn drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_withdrawn_drugs

    Branded version withdrawn by originator in several countries in 2007 for hepatotoxicity. Generic versions available. Still available in US market. Nialamide: 1974 UK, US Hepatotoxicity, drug intereaction. [3] Nikethamide: 1988 multiple markets CNS Stimulation. [3] Nitrefazole: 1984 Germany Hepatic and hematologic toxicity. [3] Nomifensine: 1981 ...

  8. List of psychotropic medications - Wikipedia

    en.wikipedia.org/wiki/List_of_psychotropic...

    Keppra (levetiracetam) – an anticonvulsant drug which is sometimes used as a mood stabilizer and has potential benefits for other psychiatric and neurologic conditions such as Tourette syndrome, anxiety disorder, and Alzheimer's disease; Klonopin – anti-anxiety and anti-epileptic medication of the benzodiazepine class

  9. ATC code N06 - Wikipedia

    en.wikipedia.org/wiki/ATC_code_N06

    ATC code N06 Psychoanaleptics is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.