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In general, proton pump inhibitors are well tolerated, and the incidence of short-term adverse effects is relatively low. The range and occurrence of adverse effects are similar for all of the PPIs, though they have been reported more frequently with omeprazole. This may be due to its longer availability and, hence, clinical experience.
Its effectiveness is similar to that of other PPIs. [6] It is taken by mouth. [4] Onset is over a few hours and effects last up to a couple of days. [4] Common side effects include constipation, abdominal pain, and nausea. [4] [3] Serious side effects may include osteoporosis, low blood magnesium, Clostridioides difficile infection, and pneumonia.
PPIs may induce common side effects including headache, diarrhoea, abdominal pain, and nausea. Taking PPI may rarely cause community-acquired pneumonia . Prolonged use of PPI may be associated with intestinal Clostridioides difficile infection , low magnesium level , Vitamin B12 and iron deficiency, osteoporosis , acute kidney inflammation, and ...
Antacids, H2 blockers (which work to reduce stomach acid), and proton pump inhibitors (PPIs) may provide relief from acid reflux symptoms. However, always consult a healthcare professional before ...
Omeprazole is a proton-pump inhibitor (PPI) and its effectiveness is similar to that of other PPIs. [9] It can be taken by mouth or by injection into a vein. [1] [10] It is also available in the fixed-dose combination medication omeprazole/sodium bicarbonate as Zegerid [11] [12] and as Konvomep. [13]
Vonoprazan, sold under the brand name Voquezna among others, is a first-in-class potassium-competitive acid blocker medication. [2] [1] Vonoprazan is used in form of the fumarate for the treatment of gastroduodenal ulcer (including some drug-induced peptic ulcers) and reflux esophagitis, and can be combined with antibiotics for the eradication of Helicobacter pylori.
Clinical studies show that ilaprazole is at least as potent a PPI as omeprazole when taken in equivalent doses. Studies also showed that ilaprazole significantly prevented the development of reflux oesophagitis. Ilaprazole is developed by Il-Yang Pharmaceutical , and is still under clinical trials with US FDA. It has launched in Korea and China ...
They have largely been replaced by drugs with fewer side effects. SSRIs (selective serotonin reuptake inhibitors), which debuted in the 1980s, work on serotonin.
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