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  2. Rivastigmine - Wikipedia

    en.wikipedia.org/wiki/Rivastigmine

    In a large clinical trial of the rivastigmine patch in 1,195 patients with Alzheimer's disease, the target dose of 9.5 mg/24-hour patch provided similar clinical effects (e.g. memory and thinking, activities of daily living, concentration) as the highest doses of rivastigmine capsules, but with one-third fewer reports of nausea and vomiting. [8]

  3. Cholinesterase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Cholinesterase_inhibitor

    Paraoxon and rivastigmine are both acetylcholinesterase inhibitors and butyrylcholinesterase inhibitors. [14] [11] [7]In 2015, the United States Food and Drug Administration's Adverse Event Reporting System database compared rivastigmine to the other ChEI drugs donepezil and galantamine found that rivastigmine was associated with a higher frequency of reports of death as an adverse event.

  4. Medication discontinuation - Wikipedia

    en.wikipedia.org/wiki/Medication_discontinuation

    Medication discontinuation is the ceasing of a medication treatment for a patient by either the clinician or the patient themself. [1] [2] When initiated by the clinician, it is known as deprescribing. [3]

  5. Acetylcholinesterase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Acetylcholinesterase_inhibitor

    When used in the central nervous system to alleviate neurological symptoms, such as rivastigmine in Alzheimer's disease, all cholinesterase inhibitors require doses to be increased gradually over several weeks, and this is usually referred to as the titration phase. Many other types of drug treatments may require a titration or stepping up phase.

  6. Transdermal patch - Wikipedia

    en.wikipedia.org/wiki/Transdermal_patch

    The patch is labelled with the time and date of administration as well as the administrator's initials. Microneedle patch size comparison [1] A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream. An advantage of a transdermal drug delivery ...

  7. Rebound effect - Wikipedia

    en.wikipedia.org/wiki/Rebound_effect

    Rebound depression may appear to arise in patients previously free of such an illness. [2] Daytime rebound effects of anxiety, metallic taste, perceptual disturbances which are typical benzodiazepine withdrawal symptoms can occur the next day after a short-acting benzodiazepine hypnotic wears off. Rebound phenomena do not necessarily only occur ...

  8. Weight loss from Lilly's Zepbound reversed after stopping ...

    www.aol.com/news/patients-lillys-zepbound-regain...

    (Reuters) -Patients on Eli Lilly's weight-loss drug Zepbound substantially regained weight nearly a year after stopping treatment, according to full results of a study published on Monday.

  9. Nonsteroidal anti-inflammatory drug - Wikipedia

    en.wikipedia.org/wiki/Nonsteroidal_anti...

    Indomethacin, ketoprofen, and piroxicam use appear to lead to the highest rate of gastric adverse effects, while ibuprofen (lower doses) and diclofenac appear to have lower rates. [ 17 ] Certain NSAIDs, such as aspirin, have been marketed in enteric-coated formulations that manufacturers claim reduce the incidence of gastrointestinal ADRs.