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In Berlin, in 1884, Gram developed a method for distinguishing between two major classes of bacteria. [1] This technique, known as Gram staining, continues to be a standard procedure of medical microbiology. This work gained Gram an international reputation. The staining method later played a major role in classifying bacteria. Gram was a ...
Gram stain (Gram staining or Gram's method), is a method of staining used to classify bacterial species into two large groups: gram-positive bacteria and gram-negative bacteria. It may also be used to diagnose a fungal infection. [1] The name comes from the Danish bacteriologist Hans Christian Gram, who developed the technique in 1884. [2]
English Developed vaccination techniques against smallpox. [2] 1818–1865 Ignaz Semmelweis: Hungarian Demonstrated that doctors washing their hands with chlorine solution significantly reduced mortality of women giving birth in hospital setting. [4] 1853–1938 Hans Christian Gram: Danish Developed the Gram stain used to identify and classify ...
The Gram stain, developed in 1884 by Hans Christian Gram, characterises bacteria based on the structural characteristics of their cell walls. [176] [77] The thick layers of peptidoglycan in the "Gram-positive" cell wall stain purple, while the thin "Gram-negative" cell wall appears pink. [176]
A major milestone in medical microbiology is the Gram stain. In 1884 Hans Christian Gram developed the method of staining bacteria to make them more visible and differentiated under a microscope. This technique is widely used today. [8]
The adjectives gram-positive and gram-negative derive from the surname of Hans Christian Gram, a Danish bacteriologist; as eponymous adjectives, their initial letter can be either capital G or lower-case g, depending on which style guide (e.g., that of the CDC), if any, governs the document being written. [23]
The stain proved popular and in 1884 was used by Hans Christian Gram to stain bacteria. He credited Paul Ehrlich for the aniline-gentian violet mixture. [ 32 ] Grübler's gentian violet was probably very similar, if not identical, to Lauth's methyl violet, which had been used as a stain by Victor André Cornil in 1875.
Japetus Steenstrup was a professor to zoologist Johan Erik Vesti Boas, who was also a student of zoologist Carl Gegenbaur, and Hans Christian Gram, inventor of the Gram stain. [ 3 ] During Charles Darwin 's extensive study of barnacles (Cirripedia) between 1846 and 1854, he corresponded with Steenstrup, who sent him both information and specimens.