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Aromatase excess syndrome (AES or AEXS) is a rarely diagnosed genetic and endocrine syndrome which is characterized by an overexpression of aromatase, the enzyme responsible for the biosynthesis of the estrogen sex hormones from the androgens, in turn resulting in excessive levels of circulating estrogens and, accordingly, symptoms of hyperestrogenism.
Aromatase deficiency is a rare condition characterized by extremely low levels or complete absence of the enzyme aromatase activity in the body. [2] It is an autosomal recessive disease resulting from various mutations of gene CYP19 (P450arom) which can lead to ambiguous genitalia and delayed puberty in females, continued linear growth into adulthood and osteoporosis in males and virilization ...
Symptoms of lavender oil poisoning by ingestion include blurred vision, difficulty breathing, burning pain in the throat, burns to the eye, confusion, decreased level of consciousness, diarrhea, stomach pain, vomiting, and rash. [16] Topical application of lavender oil may cause contact dermatitis. [18]
Potentiates CNS sedatives, [3] chronic use might cause a reversible dry skin condition. [18] Khat: qat Catha edulis: Chronic liver dysfunction [3] [19] Kratom: Mitragyna speciosa: Hepatotoxicity [20] [19] Liquorice root Glycyrrhiza glabra: Hypokalemia, hypertension, arrhythmias, edema [5] Lobelia: asthma weed, pukeweed, vomit wort Lobelia inflata
Males may also experience issues in sperm motility and morphology, which means the sperm are less likely to make it to the egg or to be able to fertilize the egg. [6] Female infertility could be a result of an issue regarding their uterus, ovaries, or fallopian tubes and can be impacted by various diseases, endocrine/hormone disruption, or ...
One important note: Excess biotin can also "cause incorrect results in certain laboratory tests that look at thyroid levels and blood markers that can help diagnose heart attacks," says Dr. Castillo.
There are signs of insulin resistance, as in PCOS in humans. [16] Due to the substantially elevated testosterone levels, there is hyperandrogenism, including masculinization of the preputial glands. [16] In addition, female αERKO mice exhibit behavior that is similar to that of males in terms of parental, aggressive, and sexual activities. [16]
The restrictions set in place were cause for hundreds of gay people to be forcibly outed and fired from the State Department. [35] The executive order was also the cause for the firing of approximately 5,000 gay people from federal employment; this included private contractors and military personnel.