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The urachus is also subject to neoplasia. Urachal adenocarcinoma is histologically similar to adenocarcinoma of the bowel. Rarely, urachus carcinomas can metastasise to other regions of the body, including pelvic bones and the lung. [7] One urachal mass has been reported that was found to be a manifestation of IgG4-related disease. [8]
If the urachus fails to close during fetal life, it can result in anatomical abnormalities such as a urachal cyst, urachal fistula, urachal diverticulum or urachal sinus. In very rare cases the urachus can fail to close fully. This can lead to a condition known as a patent urachus (also urachal fistula). Although it is mainly immediately ...
A urachal fistula is a congenital disorder caused by the persistence of the allantois (later, urachus), the structure that connects an embryo's bladder to the yolk sac. Normally, the urachus closes off to become the median umbilical ligament ; however, if it remains open, urine can drain from the bladder to an opening by the umbilicus .
4. Urinary bladder. 5. Urachus. cl. Cloaca. cp. Elevation which becomes clitoris or penis. i. Lower part of the intestine. ls. Fold of integument from which the labia majora or scrotum are formed. m, m. Right and left Müllerian ducts uniting together and running with the Wolffian ducts in gc, the genital cord. ot.
Umbilical urachal sinus. Umbilical-urachal sinus is a congenital disorder of the urinary bladder caused by failure of obliteration of proximal or distal part of the allantois, and the presentation of this anomaly is more common in children and rarer in adults.
These abnormalities are treated after draining the fetus's bladder to test a urine sample, according to Johns Hopkins Medicine. Sometimes, stents are also used to drain extra fluid from the fetus ...
During fetal development, the allantois becomes the urachus, a duct between the bladder and the yolk sac. A patent allantois can result in a urachal cyst. Because the allantois can be cultured ex vivo, it has utility as a model system for studying the formation of blood vessels as well as considerable usefulness in drug screening. [9]
A urachal diverticulum (also vesicourachal diverticulum) is a congenital disorder caused by the partial persistence of the allantois. The allantois, which later becomes the urachus , connects an embryo's bladder to the yolk sac .