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The Allen Mouse Brain Atlas is a comprehensive genome-wide map of the adult mouse brain that reveals where each gene is expressed. [3] The mouse brain atlas was the original project of the Allen Brain Atlas and was finished in 2006. The purpose of the atlas is to aid in the development of neuroscience research.
The house mouse (Mus musculus) has a gestation period of 19 to 21 days. Key events in mouse brain development occur both before and after birth, beginning with peak neurogenesis of the cranial motor nuclei 9 days after conception, up to eye opening which occurs after birth and about 30 days after conception.
Named the Allen Brain Atlas, it was a web-based, three-dimensional map of gene expression in the mouse brain detailing more than 21,000 genes at the cellular level. Since the project's launch, it has been renamed the Allen Mouse Brain Atlas to distinguish it from subsequent atlas projects.
Allen Brain Atlas [2] Mouse Brain Library [3] High resolution mouse brain atlas; BrainMaps. High-Resolution Brain Maps and Brain Atlases of Mus musculus; Despite superficial differences, especially in size and weight, the mouse brain and its function can serve as a powerful animal model for study of human brain diseases or mental disorders (see ...
Scientists have created a full map of an adult brain for the first time.. The 3D model of all of the neurons of a fruit fly, and the 50 million connections between them, is the first time that ...
Epigenetic modifications play a key role in regulating gene expression in differentiating neural stem cells and are critical for cell fate determination in the developing and adult mammalian brain. Epigenetic modifications include DNA cytosine methylation to form 5-methylcytosine and 5-methylcytosine demethylation .
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Fate mapping shows which tissues come from which part of the embryo at a certain stage in development, whereas cell lineage shows the relationships between cells at each division. [12] A cell lineage can be used to generate a fate map, and in cases like C. elegans, successive fate mapping can be used to develop a cell lineage. [13]