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The meaning of MINIMUM DOSE is the smallest dose of a medicine or drug that will produce an effect.
The minimum effective dose is the smallest amount of a drug that produces the desired therapeutic effect in patients. Understanding this concept is crucial when evaluating drug efficacy, as it helps determine the lowest dosage needed for a medication to be effective without causing adverse effects.
1. the air dose of radiation at the skin surface, comprising the primary radiation plus backscatter. 2. the absorbed dose in the skin. threshold dose the minimum dose of ionizing radiation, a chemical, or a drug that will produce a detectable degree of any given effect.
People ages 65 years and older, vaccinated under the routine schedule, are recommended to receive 2 doses of any 2024–2025 COVID-19 vaccine (i.e., Moderna, Novavax, or Pfizer-BioNTech) separated by 6 months (minimum interval 2 months) regardless of vaccination history, with one exception: Unvaccinated people who initiate vaccination with 2024 ...
The concept of the minimum dose relates to the Arndt-Schultz law (named after the pharmacologist Hugo Schultz and the psychiatrist Rudolf Arndt, who formulated the law). The law applies to both pharmaca (active ingredients that prevent, treat or cure disease) and poisons, and states that:
Vaccine doses administered ≤4 days before the minimum age or interval are considered valid. Doses of any vaccine administered ≥5 days earlier than the minimum age or minimum interval should not be counted as valid and should be repeated.
Typically, metformin treatment starts with a lower dose, such as 500 milligrams (mg) twice daily or 850 mg once daily. The exact dosage is tailored based on individual health factors under the guidance of a healthcare professional. For adults, the daily metformin dosage should not exceed 2,550 mg.