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The most common type in Canada and the United States is a three-ring system for letter size pages (8 + 1 ⁄ 2 by 11 inches or 220 mm × 280 mm), whose size is similar to ISO 216-based A4 size. A standard 8 + 1 ⁄ 2 by 11 inches (220 mm × 280 mm) sheet of paper has three holes with spacing of 4 + 1 ⁄ 4 inches (110 mm).
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Capillary refill time (CRT) is defined as the time taken for color to return to an external capillary bed after pressure is applied to cause blanching. [3] It can be measured by holding a hand higher than heart-level and pressing the soft pad of a finger or fingernail until it turns white, then taking note of the time needed for the color to ...
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