Search results
Results from the WOW.Com Content Network
A foreign-body giant cell is a collection of fused macrophages which are generated in response to the presence of a large foreign body. This is particularly evident with catheters , parasites , or biomaterials that are inserted into the body for replacement or regeneration of diseased or damaged tissues.
Foreign body granuloma formation consists of protein adsorption, macrophages, multinucleated foreign body giant cells (macrophage fusion), fibroblasts, and angiogenesis. It has also been proposed that the mechanical property of the interface between an implant and its surrounding tissues is critical for the host response.
A giant cell (also known as a multinucleated giant cell, or multinucleate giant cell) is a mass formed by the union of several distinct cells (usually histiocytes), often forming a granuloma. [ 1 ] Although there is typically a focus on the pathological aspects of multinucleate giant cells (MGCs), they also play many important physiological roles.
Foreign body materials are very specific for foreign body granuloma. Granuloma annulare: Palisading granuloma and mucin Necrobiosis lipoidica: Palisading granuloma and necrobiotic materials Foreign-body granuloma: Foreign body Juvenile xanthogranuloma: Touton type giant cells and foamy cells VI. Tumoral lesions: Benign tumoral lesions Mastocytoma
Epithelioid cell granuloma can be defined as specifically and structurally organized collection of epithelioid cells, macrophages, lymphocytes and dendritic cells. Foreign-body granulomas may be considered an organized collection of macrophages, including mere collections of giant cells surrounding inert substances like suture material – the ...
An asteroid body is a microscopic finding seen within the giant cells of granulomas in diseases such as sarcoidosis and foreign-body giant cell reactions. [1] There is controversy about their composition. Traditionally, they were thought to be cytoskeletal elements and to consist primarily of vimentin. [2]
Areas of the cervix that turn white (acetowhiteness) after the application of acetic acid or have an abnormal vascular pattern are often considered for biopsy. If no lesions are visible, an iodine solution may be applied to the cervix to help highlight areas of abnormality. [citation needed]
The large lipid-laden macrophages display an eosinophilic or clear cytoplasm with a granular and vacuolated quality but can also have a spindle shape. Foreign body-type and Touton-type giant cells, calcospherites, cholesterol clefts and hemosiderin deposits are additional findings. [citation needed]