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Naltrexone/bupropion, sold under the brand name Contrave among others, is a fixed-dose combination medication for the management of chronic obesity in adults in combination with a reduced-calorie diet and increased physical activity. [4] [6] It contains naltrexone, an opioid antagonist, and bupropion, an aminoketone atypical antidepressant. [4]
Bupropion, when used for treating long-term weight gain over six to twelve months, results in an average weight loss of 2.7 kilograms (6.0 lb) over placebo. [74] This is not much different from the weight loss produced by several other weight-loss medications such as sibutramine or orlistat . [ 74 ]
For example, a study published in the Journal of Clinical Medicine in 2016 found that bupropion users lost an average of 7.1 pounds over the course of two years when compared to depressed people ...
Here’s what to keep in mind about type 2 diabetes medications used to support weight loss and weight loss injections: Weight loss injections are safe and effective when used as prescribed .
In addition, about 15–30% of participants had weight measurements exactly at the 6-month, 1-year, and 2-year marks, and only 40% to 50% had weight measurements at one time point or more. This ...
It now recommends considering the use of weight loss medication in some overweight children aged 12 or older. [47] The European Medicines Agency has approved semaglutide for children aged 12 or older who have a BMI in the 95 percentile for their age and a weight of at least 60 kilograms (130 lb).
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