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Brotizolam [3] (marketed under brand name Lendormin) is a sedative-hypnotic [4] thienotriazolodiazepine [5] drug which is a benzodiazepine analog. [6] It possesses anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties, and is considered to be similar in effect to other short-acting hypnotic benzodiazepines such as triazolam or midazolam. [7]
Finally, note that the benzodiazepine core is a privileged scaffold, which has been used to derive drugs with diverse activity that is not limited to the GABA A modulatory action of the classical benzodiazepines, [60] such as devazepide and tifluadom, however these have not been included in the list below. 2,3-benzodiazepines such as tofisopam ...
A study in 2000 found that long-term benzodiazepine therapy does not result in brain abnormalities. [75] Withdrawal from high-dose use of nitrazepam anecdotally was alleged in 2001 to have caused severe shock of the whole brain with diffuse slow activity on EEG in one patient after 25 years of use. After withdrawal, abnormalities in hypofrontal ...
Most women over 60 have entered a new phase in life and health: post-menopause. ... Scott notes that bone loss is the most dramatic within three years of a woman's last period. “Vaginal dryness ...
Now, seven years after my diagnosis, I wish I could have told my 22-year-old self that living with a chronic illness isn’t a bad thing and life isn’t over. Even though it felt like the end of ...
This sedative -related article is a stub. You can help Wikipedia by expanding it.
Core structure of thienotriazolodiazepines. A thienotriazolodiazepine [1] is a heterocyclic compound containing a diazepine ring fused to thiophene and triazole rings. . Thienotriazolodiazepine forms the central core of several pharmaceutical drugs
Usually, PMR only affects adults over the age of 50. [2] [21] The average age of a person who has PMR is about 70 years old, [13] [27] with the highest prevalence in those older than 70. [2] Women are three times as likely to get PMR as men. [2] People of Western and Northern European descent are more likely to get this disease. [13]
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