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The middle region is a mostly fibrous portion. It consists of two layers: the endosteal layer, which lies closest to the skull, and the inner meningeal layer, which lies closer to the brain. [7] It contains larger blood vessels that split into the capillaries in the pia mater. It is composed of dense fibrous tissue, and its inner surface is ...
The meninges comprise three membranes that, together with the cerebrospinal fluid, enclose and protect the brain and spinal cord (the central nervous system). The pia mater is a delicate impermeable membrane that firmly adheres to the surface of the brain, following all the minor contours.
The arachnoid mater is interposed between the two other meninges, the more superficial (closer to the surface) and much thicker dura mater and the deeper pia mater, from which it is separated by the subarachnoid space. The delicate arachnoid layer is not attached to the inside of the dura but against it, and surrounds the brain and spinal cord.
The membrane in this area is much thicker than the cranial pia mater, due to the two-layer composition of the pia membrane. The outer layer, which is made up of mostly connective tissue, is responsible for this thickness. Between the two layers are spaces which exchange information with the subarachnoid cavity as well as blood vessels.
The dura mater has two layers, an outer periosteal layer closely adhered to the neurocranium, and an inner meningeal layer known as the dural border cell layer. [1] The two dural layers are for the most part fused together forming a thick fibrous tissue membrane that covers the brain and the vertebrae of the spinal column. [2]
In the skull, the periosteal layer of the dura mater adheres to the inner surface of the skull bones while the meningeal layer lays over the arachnoid mater. Between them is the epidural space . The two layers of the dura mater separate at several places, with the meningeal layer projecting deeper into the brain parenchyma forming fibrous septa ...
The latter is the thickest and outermost of the three membrane layers; it contains the most collagen, and it is derived from the mesoderm - the middle germ layer or the primary layer of the cells formed in embryogenic development via epigenetic effects induced by developmental cues, in the early embryo. Also there are the two parietal bones and ...
The middle meningeal artery is the largest of the three (paired) arteries that supply the meninges, the others being the anterior meningeal artery and the posterior meningeal artery. The anterior branch of the middle meningeal artery runs beneath the pterion. It is vulnerable to injury at this point, where the skull is thin.