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Kaopectate is an orally taken medication from Jonathan Jordan for the treatment of mild diarrhea. It is also sometimes used to treat indigestion, nausea, and stomach ulcers. The active ingredients have varied over time, and are different between the United States and Canada. The original active ingredients were kaolinite and pectin.
Paregoric was a household remedy in the 18th and 19th centuries when it was widely used to control diarrhea in adults and children, as an expectorant and cough medicine, to calm fretful children, and to rub on the gums to counteract the pain from teething. A formula for paregoric from Dr. Chase's Recipes (1865): [7]
Electrolyte solutions, while not true antidiarrheals, are used to replace lost fluids and salts in acute cases.; Bulking agents like methylcellulose, guar gum or plant fibre (bran, sterculia, isabgol, etc.) are used for diarrhoea in functional bowel disease and to control ileostomy output.
Preliminary clinical data suggests ginger may be effective for treatment of nausea and/or vomiting in a number of settings. [19] [20] [21] Emetrol is also claimed to be an effective antiemetic. Propofol is given intravenously. It has been used in an acute care setting in hospital as a rescue therapy for emesis. [22]
Racecadotril, also known as acetorphan, is an antidiarrheal medication which acts as a peripheral enkephalinase inhibitor. [3] Unlike other opioid medications used to treat diarrhea, which reduce intestinal motility, racecadotril has an antisecretory effect — it reduces the secretion of water and electrolytes into the intestine. [3]
Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, migraines, or surgery. [8] It is also effective for treating gastroenteritis. [9] [10] It can be given orally (by mouth), intramuscularly (injection into a muscle), or intravenously ...
Loperamide/simethicone is combination medication sold under the brand name Imodium Multi-Symptom Relief (formerly Imodium A-D Advanced) used to treat diarrhea and gas simultaneously. It is manufactured by the McNeil Consumer Healthcare Division of McNeil PPC, Inc. It contains loperamide and simethicone.
The medication provides relief from nausea by blocking D 2 receptors in the chemoreceptor trigger zone and from gastrointestinal symptoms by blocking D 2 receptors in the gut. [ 20 ] [ 2 ] It blocks D 2 receptors in the lactotrophs of the anterior pituitary gland increasing release of prolactin which in turn increases lactation .
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