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Pantothenic acid (vitamin B 5) is a B vitamin and an essential nutrient. [6] All animals need pantothenic acid in order to synthesize coenzyme A (CoA), which is essential for cellular energy production and for the synthesis and degradation of proteins, carbohydrates, and fats. [6] [7] Pantothenic acid is the combination of pantoic acid and β ...
Panthenol (also called pantothenol) is the alcohol analog of pantothenic acid (vitamin B 5), and is thus a provitamin of B 5. In organisms, it is quickly oxidized to pantothenic acid. It is a viscous transparent liquid at room temperature. Panthenol is used in pharmaceutical and children's products as a moisturizer and to hasten wound healing.
Pantothenic acid is involved in the oxidation of fatty acids and carbohydrates. Coenzyme A, which can be synthesised from pantothenic acid, is involved in the synthesis of amino acids, fatty acids, ketone bodies, cholesterol, [15] [better source needed] phospholipids, steroid hormones, neurotransmitters (such as acetylcholine), and antibodies. [16]
The SMVT is a transporter for pantothenic acid (vitamin B5) and biotin (vitamin B7) at the blood–brain barrier. [8] It is also a transporter for lipoic acid [9] and iodide. Transport of these nutrients is competitive [10] and a surplus of a given nutrient may saturate the transporter and prevent the uptake of other nutrients.
Pharmacognosy is the study of crude drugs obtained from medicinal plants, animals, fungi, and other natural sources. [1] The American Society of Pharmacognosy defines pharmacognosy as "the study of the physical, chemical, biochemical , and biological properties of drugs, drug substances, or potential drugs or drug substances of natural origin ...
Natural sources may lead to basic research on potential bioactive components for commercial development as lead compounds in drug discovery. [12] Although natural products have inspired numerous drugs, drug development from natural sources has received declining attention in the 21st century by pharmaceutical companies, partly due to unreliable ...
Pantethine (bis-pantethine or co-enzyme pantethine) is a dimeric form of pantetheine, which is produced from pantothenic acid (vitamin B 5) by the addition of cysteamine. Pantethine was discovered by Gene Brown, a PhD student at the time. Pantethine is two molecules of pantetheine linked by a disulfide bridge.
The omega-3 eicosapentaenoic acid (EPA), which can be made in the human body from the omega-3 essential fatty acid alpha-linolenic acid (ALA), or taken in through marine food sources, serves as a building block for series 3 prostaglandins (e.g., weakly inflammatory PGE3).
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