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UGT2B7 (UDP-Glucuronosyltransferase-2B7) is a phase II metabolism isoenzyme found to be active in the liver, kidneys, epithelial cells of the lower gastrointestinal tract and also has been reported in the brain. In humans, UDP-Glucuronosyltransferase-2B7 is encoded by the UGT2B7 gene. [5] [6]
Uridine 5'-diphospho-glucuronosyltransferase (UDP-glucuronosyltransferase, UGT) is a microsomal glycosyltransferase (EC 2.4.1.17) that catalyzes the transfer of the glucuronic acid component of UDP-glucuronic acid to a small hydrophobic molecule. This is a glucuronidation reaction. [2] [3] Alternative names: glucuronyltransferase; UDP ...
UDP glucuronosyltransferase 1 family, polypeptide A7 is a protein that in humans is encoded by the UGT1A7 gene. [ 5 ] This gene encodes a UDP-glucuronosyltransferase , an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids , bilirubin , hormones , and drugs, into water-soluble, excretable metabolites.
UDP-glucuronosyltransferase 1-1 also known as UGT-1A is an enzyme that in humans is encoded by the UGT1A1 gene. [5] [6]UGT-1A is a uridine diphosphate glucuronosyltransferase (UDP-glucuronosyltransferase, UDPGT), an enzyme of the glucuronidation pathway that transforms small lipophilic (fat-soluble) molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable ...
Glucuronidation consists of transfer of the glucuronic acid component of uridine diphosphate glucuronic acid to a substrate by any of several types of UDP-glucuronosyltransferase. UDP-glucuronic acid (glucuronic acid linked via a glycosidic bond to uridine diphosphate ) is an intermediate in the process and is formed in the liver .
n/a Ensembl n/a n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a Wikidata View/Edit Human UDP glucuronosyltransferase 1 family, polypeptide A cluster (UGT1A) is a human gene locus that includes several UDP glucuronosyltransferases. The UGT1A locus includes thirteen unique alternate first exons followed by four common exons. Four of ...
54578 394435 Ensembl ENSG00000167165 ENSMUSG00000090145 UniProt P19224 K9J7B2 RefSeq (mRNA) NM_205862 NM_001072 NM_201410 RefSeq (protein) NP_001063 NP_995584 NP_958812 Location (UCSC) Chr 2: 233.69 – 233.77 Mb Chr 1: 88.03 – 88.15 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse UDP-glucuronosyltransferase 1-6 is an enzyme that in humans is encoded by the UGT1A6 gene. Function ...
UDP glucuronosyltransferase 2 family, polypeptide B4, also known as UGT2B4, is an enzyme that in humans is encoded by the UGT2B4 gene. [5] [6] [7] Function.