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  2. Why You Feel That Burning Sensation in Your Legs During Hard ...

    www.aol.com/why-feel-burning-sensation-legs...

    Experts clear up the confusion on lactic acid, the burning sensation you feel in ... lactate threshold and being just below. “I like having athletes do four sets of three to five minutes spent ...

  3. Muscle weakness - Wikipedia

    en.wikipedia.org/wiki/Muscle_weakness

    The insufficiency of energy, i.e. sub-optimal aerobic metabolism, generally results in the accumulation of lactic acid and other acidic anaerobic metabolic by-products in the muscle, causing the stereotypical burning sensation of local muscle fatigue, though recent studies have indicated otherwise, actually finding that lactic acid is a source ...

  4. Weakness - Wikipedia

    en.wikipedia.org/wiki/Weakness

    The insufficiency of energy, i.e. sub-optimal aerobic metabolism, generally results in the accumulation of lactic acid and other acidic anaerobic metabolic by-products in the muscle, causing the stereotypical burning sensation of local muscle fatigue, though recent studies have indicated otherwise, actually finding that lactic acid is a source ...

  5. Lactic acidosis - Wikipedia

    en.wikipedia.org/wiki/Lactic_acidosis

    Undissociated lactic acid can cross the rumen wall to the blood, [29] where it dissociates, lowering blood pH. Both L and D isomers of lactic acid are produced in the rumen; [24] these isomers are metabolized by different metabolic pathways, and activity of the principal enzyme involved in metabolism of the D isomer declines greatly with lower ...

  6. Dysesthesia - Wikipedia

    en.wikipedia.org/wiki/Dysesthesia

    It is sometimes described as feeling like acid under the skin. Burning dysesthesia might accurately reflect an acidotic state in the synapses and perineural space. Some ion channels will open to a low pH, and the acid sensing ion channel has been shown to open at body temperature, in a model of nerve injury pain. Inappropriate, spontaneous ...

  7. Muscle fatigue - Wikipedia

    en.wikipedia.org/wiki/Muscle_fatigue

    It was once believed that lactic acid build-up was the cause of muscle fatigue. [8] The assumption was lactic acid had a "pickling" effect on muscles, inhibiting their ability to contract. Though the impact of lactic acid on performance is now uncertain, it may assist or hinder muscle fatigue.

  8. Delayed onset muscle soreness - Wikipedia

    en.wikipedia.org/wiki/Delayed_onset_muscle_soreness

    This increases the risk of broadening, smearing, and damage to the sarcomere. When microtrauma occurs to these structures, nociceptors (pain receptors) within the muscle's connective tissues are stimulated and cause a sensation of pain. [7] Another explanation for the pain associated with DOMS is the "enzyme efflux" theory.

  9. Adenosine monophosphate deaminase deficiency type 1

    en.wikipedia.org/wiki/Adenosine_monophosphate...

    In contrast, while muscle glycogen is available, accumulation of lactic acid in this situation would produce a noticeable sensation. On the other hand, in persons with balanced AMPD and myophosphorylase activities in muscle cells, lactic acid and ammonia are produced simultaneously, counteracting each other's effects to some degree.