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  2. Gabapentin - Wikipedia

    en.wikipedia.org/wiki/Gabapentin

    By binding to α 2 δ-1, gabapentin reduces the release of excitatory neurotransmitters (primarily glutamate) and as a result, reduces excess excitation of neuronal networks in the spinal cord and brain. Sleepiness and dizziness are the most common side effects. Serious side effects include respiratory depression, and allergic reactions. [7]

  3. Gabapentinoid - Wikipedia

    en.wikipedia.org/wiki/Gabapentinoid

    A generic version of gabapentin first became available in the United States in 2004. [46] An extended-release formulation of gabapentin for once-daily administration, under the brand name Gralise, was approved in the United States for the treatment postherpetic neuralgia in January 2011. [47] [48]

  4. Common sleep medication may prevent brain from clearing 'waste'

    www.aol.com/common-sleep-medication-may-prevent...

    In a mouse study, researchers found that zolpidem (Ambien), a common sleep aid, could prevent the brain from effectively clearing up 'waste', though it remains unclear whether this could affect ...

  5. Anticonvulsant - Wikipedia

    en.wikipedia.org/wiki/Anticonvulsant

    The newer drugs tend to have fewer side effects. [42] For newly diagnosed partial or mixed seizures, there is evidence for using gabapentin, lamotrigine, oxcarbazepine or topiramate as monotherapy. [42] Lamotrigine can be included in the options for children with newly diagnosed absence seizures. [42]

  6. Can Gabapentin Really Cause ED? - AOL

    www.aol.com/lifestyle/gabapentin-really-cause-ed...

    The link between gabapentin and ED may be due to gabapentin’s effects on neurotransmitters. Gabapentin is also associated with other intimate side effects, like difficulty reaching orgasm ...

  7. GABA reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/GABA_reuptake_inhibitor

    It is used as a treatment for partial seizures in adults and children over 12, and works by amplifying GABA's calming effects in the brain. This, however, comes with potential drawbacks. While generally well-tolerated, some users experience concentration issues, language difficulties, and even a higher risk of depression, hallucinations, and ...

  8. Is 4 hours of sleep enough? What sleeping too little does to ...

    www.aol.com/news/4-hours-sleep-enough-sleeping...

    Is 4 hours of sleep enough? Experts explain what happens to your body when you sleep four hours, health effects of sleep deprivation and tips to improve sleep.

  9. Kindling (sedative–hypnotic withdrawal) - Wikipedia

    en.wikipedia.org/wiki/Kindling_(sedative...

    Failure to manage the alcohol withdrawal syndrome appropriately can lead to permanent brain damage or death. [11] Acamprosate, a drug used to promote abstinence from alcohol, an NMDA antagonist drug, reduces excessive glutamate activity in the central nervous system and thereby may reduce excitotoxicity and withdrawal related brain damage. [12 ...

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