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Glycerin suppositories used as laxatives. Laxatives, purgatives, or aperients are substances that loosen stools [1] and increase bowel movements. They are used to treat and prevent constipation. Laxatives vary as to how they work and the side effects they may have.
Two suppositories can be inserted at once if a very strong, purgative, enema-like result is needed. A few hours after the initial evacuation, there can be a secondary action which will continue as long as there is unexpelled bisacodyl present in the rectum. As a commercially prepared micro-enema, it is usually effective in 5 to 20 minutes. [7]
A suppository, a solid drug delivery system inserted into the rectum, where it dissolves or melts to exert local or systemic effects. A micro-enema , a small amount (usually less than 10 millilitres) of a liquid -drug solution injected into the rectum.
Enemas (such as hyperosmotic saline) and suppositories (such as glycerine suppositories) work by increasing water content and stimulating peristalsis to aid in expulsion, and both work much more quickly than oral laxatives. Because enemas work in 2–15 minutes, they do not allow sufficient time for a large fecal mass to soften.
A suppository is a dosage form used to deliver medications by insertion into a body orifice (any opening in the body), where it dissolves or melts to exert local or systemic effects. There are three types of suppositories, each to insert into a different sections: rectal suppositories into the rectum , vaginal suppositories into the vagina ...
A rudimentary form of "dry" enema is the use of a non-medicated glycerin suppository. [1] However, due to the relative hardness of the suppository – necessary for its insertion into the human body – before glycerin can act, it must be melted by the heat of the body, and hence it does not take effect for up to an hour.
It is a weaker laxative than bisacodyl and castor oil. [1] Common side effects of senna glycoside include abdominal cramps. [3] It is not recommended for long-term use, as it may result in poor bowel function or electrolyte problems. [1] While no harm has been found to result from use while breastfeeding, such use is not typically recommended. [1]
The Macy Catheter is a specialized catheter designed to provide comfortable and discreet administration of ongoing medications via the rectal route. The catheter was developed to make rectal access more practical and provide a way to deliver and retain liquid formulations in the distal rectum so that health practitioners can leverage the established benefits of rectal administration.