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Nitric acid, with a pK value of around −1.7, behaves as a strong acid in aqueous solutions with a pH greater than 1. [23] At lower pH values it behaves as a weak acid. pK a values for strong acids have been estimated by theoretical means. [24] For example, the pK a value of aqueous HCl has been estimated as −9.3.
Salicylic acid is an organic compound with the formula HOC 6 H 4 COOH. [3] A colorless (or white), bitter-tasting solid, it is a precursor to and a metabolite of acetylsalicylic acid (aspirin). [3] It is a plant hormone, [8] and has been listed by the EPA Toxic Substances Control Act (TSCA) Chemical Substance Inventory as an experimental ...
Aspirin is the genericized trademark for acetylsalicylic acid (ASA), a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, fever, and inflammation, and as an antithrombotic. [10] Specific inflammatory conditions that aspirin is used to treat include Kawasaki disease , pericarditis , and rheumatic fever .
In chemistry and biochemistry, the Henderson–Hasselbalch equation = + ([] []) relates the pH of a chemical solution of a weak acid to the numerical value of the acid dissociation constant, K a, of acid and the ratio of the concentrations, [] [] of the acid and its conjugate base in an equilibrium.
The first (e.g., acetic acid or ammonium) have only one dissociable group, the second (e.g., carbonic acid, bicarbonate, glycine) have two dissociable groups and the third (e.g., phosphoric acid) have three dissociable groups. In the case of multiple pK values they are designated by indices: pK 1, pK 2, pK 3 and so on.
The term "acetyl" was coined by the German chemist Justus von Liebig in 1839 CE to describe what he incorrectly believed to be the radical of acetic acid (the main component of vinegar, aside from water), which is now known as the vinyl group (coined in 1851 CE); "acetyl" is derived from the Latin acētum, meaning "vinegar."
The therapeutic effects of salicylic acids were first documented in 1763 by Edward Stone, with acetylsalicylic acid being synthesized by Felix Hoffmann, a chemist working under Bayer, in 1897. [4] Acetylsalicylic acid-derived salt compounds were first discovered in 1970, [5] and the synthesis of lysine acetylsalicylate was first documented in ...
While the value measures the tendency of an acidic solute to transfer a proton to a standard solvent (most commonly water or DMSO), the tendency of an acidic solvent to transfer a proton to a reference solute (most commonly a weak aniline base) is measured by its Hammett acidity function, the value. Although these two concepts of acid strength ...