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The risk factors [110] for treatment resistant depression are: the duration of the episode of depression, severity of the episode, if bipolar, lack of improvement in symptoms within the first couple of treatment weeks, anxious or avoidant and borderline comorbidity and old age. Treatment resistant depression is best handled with a combination ...
Antidepressants are recommended by the UK National Institute for Health and Care Excellence (NICE) as a first-line treatment of severe depression and for the treatment of mild-to-moderate depression that persists after conservative measures such as cognitive therapy. [10]
This article needs to be updated. The reason given is: Many outdated sources and information (older than five years). Please help update this article to reflect recent events or newly available information. (July 2024) Medical condition Major depressive disorder Other names Clinical depression, major depression, unipolar depression, unipolar disorder, recurrent depression Sorrowing Old Man (At ...
The UK National Institute for Health and Care Excellence (NICE)'s 2022 guidelines indicate that antidepressants should not be routinely used for the initial treatment of mild depression, "unless that is the person's preference". [29] The guidelines recommended that antidepressant treatment be considered:
[40] [41] In 2014 the UK National Institute for Health and Care Excellence (NICE) recommended preventive CBT for people at risk of psychosis. [22] [23] There is also tentative evidence that treatment may help those with early symptoms. [42] [43] Antipsychotic medications are not recommended for preventing psychosis. [22]
In February 2006 NICE recommended that CCBT be made available for use within the NHS across England and Wales for patients presenting with mild-to-moderate depression, rather than immediately opting for antidepressant medication, [203] and CCBT is made available by some health systems. [216]
The treatment of a major depressive episode can be split into three phases: [27] Acute phase: the goal of this phase is to resolve the current major depressive episode. Continuation: this phase continues the same treatment from the acute phase for 4–8 months after the depressive episode has resolved, and the goal is to prevent relapse.
The work that NICE is involved in, attracts the attention of many groups, including doctors, the pharmaceutical industry, and patients. NICE is often associated with controversy, because the requirement to make decisions at a national level, can conflict with what is (or is believed to be) in the best interests of an individual patient.
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