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The Allen Mouse Brain Atlas is a comprehensive genome-wide map of the adult mouse brain that reveals where each gene is expressed. [3] The mouse brain atlas was the original project of the Allen Brain Atlas and was finished in 2006. The purpose of the atlas is to aid in the development of neuroscience research.
The house mouse (Mus musculus) has a gestation period of 19 to 21 days. Key events in mouse brain development occur both before and after birth, beginning with peak neurogenesis of the cranial motor nuclei 9 days after conception, up to eye opening which occurs after birth and about 30 days after conception.
The amount of time required to generate all the neurons of the CNS varies widely across mammals, and brain neurogenesis is not always complete by the time of birth. [3] For example, mice undergo cortical neurogenesis from about embryonic day (post-conceptional day) (E)11 to E17, and are born at about E19.5. [9]
Besides the human brain, [4] brain atlases exist for the brains of the mouse, [5] rhesus macaques, [6] Drosophila, [7] pig [8] and others. Notable examples include the Allen Brain Atlas , BrainMaps , BigBrain , Infant Brain Atlas , [ 9 ] and the work of the International Consortium for Brain Mapping (ICBM).
Allen Brain Atlas [2] Mouse Brain Library [3] High resolution mouse brain atlas; BrainMaps. High-Resolution Brain Maps and Brain Atlases of Mus musculus; Despite superficial differences, especially in size and weight, the mouse brain and its function can serve as a powerful animal model for study of human brain diseases or mental disorders (see ...
It is hypothesized in [66] that the growing structure copies the axonal development of the human brain: the earliest developing connections (axonal fibers) are common at most of the subjects, and the subsequently developing connections have larger and larger variance, because their variances are accumulated in the process of axonal development.
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The development of sensory maps requires learning, long term potentiation, experience-dependent plasticity, and innate characteristics. [1] There is significant evidence for experience-dependent development and maintenance of sensory maps, and there is growing evidence on the molecular basis, synaptic basis and computational basis of experience ...