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Pulsed field ablation (PFA) is a non-thermal (not using extreme heat or cold) method of biological ablation (removal of structure or functionality) utilizing high-amplitude pulsed (microsecond duration) electric fields to create irreversible electroporation in tissues. [1] [2] It is used most widely to treat tumors or cardiac arrhythmias. [3]
Transurethral needle ablation can be used to treat benign prostatic hyperplasia (BPH). [ 4 ] Some clinical studies have reported that TUNA is safe and effective, improving the urine flow with minimal side effects when compared with other procedures, such as transurethral resection of the prostate (TURP) and open prostatectomy .
Transurethral microwave thermotherapy is a non-surgical, minimally invasive therapy that can be performed under a local anesthetic on an outpatient basis. The treatment involves inserting a special microwave urinary catheter into the hyperplastic prostatic urethra.
The duty cycle for a pulsed radio frequency is the percent time the RF packet is on, 4.2% for this example ([0.042 ms × 1000 pulses divided by 1000 ms/s] × 100). The pulse packet form can be a square, triangle, sawtooth or sine wave. [1] In several applications of pulse radio frequency, such as radar, [2] times between pulses can be modulated.
Radio frequencies at non-ablation energy levels are commonly used as a part of aesthetic treatments that can tighten skin, reduce fat by lipolysis and also apoptosis, [4] or promote healing. [5] RF diathermy is a medical treatment that uses RF induced heat as a form of physical therapy and in surgical procedures. It is commonly used for muscle ...
Transurethral needle ablation (TUNA) operates with a different type of energy, radio frequency (RF) energy, but is designed along the same premise as TUMT devices, that the heat the device generates will cause necrosis of the prostatic tissue and shrink the prostate. The TUNA device is inserted into the urethra using a rigid scope much like a ...
Radiofrequency ablation (RFA) and cryoablation have been used since the 1990s; however, in lesions larger than 3 cm, their efficacy is limited. The newer ablation modalities, such as IRE, microwave ablation (MWA), and high-intensity focused ultrasound, may help overcome the challenges in tumor size. [92]
Interventional radiologists have started to treat prostate cancer with minimally invasive therapies such as cryoablation, HIFU, radiofrequency ablation, and photodynamic therapy that permit focal therapy by utilizing image guidance. These therapies are still in beginning or experimental stages; however, because they preserve tissue, they can ...
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