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Pulsed field ablation (PFA) is a non-thermal (not using extreme heat or cold) method of biological ablation (removal of structure or functionality) utilizing high-amplitude pulsed (microsecond duration) electric fields to create irreversible electroporation in tissues. [1] [2] It is used most widely to treat tumors or cardiac arrhythmias. [3]
Transurethral needle ablation can be used to treat benign prostatic hyperplasia (BPH). [ 4 ] Some clinical studies have reported that TUNA is safe and effective, improving the urine flow with minimal side effects when compared with other procedures, such as transurethral resection of the prostate (TURP) and open prostatectomy .
Transurethral microwave thermotherapy is a non-surgical, minimally invasive therapy that can be performed under a local anesthetic on an outpatient basis. The treatment involves inserting a special microwave urinary catheter into the hyperplastic prostatic urethra.
While thermal radiofrequency ablation for tumors and cardiac arrhythmia has been used for over 25 years, non-thermal pulsed radio frequency is currently being developed for the ablation of cardiac arrhythmias and tumors. The technique uses pulsed radio frequency energy delivered via catheter at frequencies of 300–750 kHz for 30 to 60 seconds ...
Radiofrequency ablation (RFA) and cryoablation have been used since the 1990s; however, in lesions larger than 3 cm, their efficacy is limited. The newer ablation modalities, such as IRE, microwave ablation (MWA), and high-intensity focused ultrasound, may help overcome the challenges in tumor size. [92]
Medical applications of radio frequency (RF) energy, in the form of electromagnetic waves (radio waves) or electrical currents, have existed for over 125 years, [1] and now include diathermy, hyperthermy treatment of cancer, electrosurgery scalpels used to cut and cauterize in operations, and radiofrequency ablation. [2]
Interventional radiologists have started to treat prostate cancer with minimally invasive therapies such as cryoablation, HIFU, radiofrequency ablation, and photodynamic therapy that permit focal therapy by utilizing image guidance. These therapies are still in beginning or experimental stages; however, because they preserve tissue, they can ...
Studies on localized prostate cancer showed that, after treatment, progression-free survival rates were high for low- and intermediate- risk patients with recurrent prostate cancer. [2] The InsighTec ExAblate 2000 was the first MRgFUS system to obtain FDA market approval, [3] US patent 5,247,935.
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