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S. mutans is the main component of the oral microbiota. [15] A healthy oral microbiome decreases oral infections and promotes a healthy gut microbiome. However, when disturbed, it can lead to gum inflammations and bad breath. [16] Dental plaque is formed when oral microorganisms form biofilms on the surfaces of teeth.
The human gut microbiota plays a crucial role in modulating the effect of the administered drugs on the human. Directly, gut microbiota can synthesize and release a series of enzymes with the capability to metabolize drugs such as microbial biotransformation of L-dopa by decarboxylase and dehydroxylase enzymes. [99]
Graphic depicting the human skin microbiota, with relative prevalences of various classes of bacteria. The human microbiome is the aggregate of all microbiota that reside on or within human tissues and biofluids along with the corresponding anatomical sites in which they reside, [1] [2] including the gastrointestinal tract, skin, mammary glands, seminal fluid, uterus, ovarian follicles, lung ...
The gut microbiota are very important for the host health because they play role in degradation of non-digestible polysaccharides (fermentation of resistant starch, oligosaccharides, inulin) strengthening gut integrity or shaping the intestinal epithelium, harvesting energy, protecting against pathogens, and regulating host immunity.
Identification of unique adaptations adopted by segmented filamentous bacteria (SFB) in their role as gut commensals. [45] SFB are medically important because they stimulate T helper 17 cells, thought to play a key role in autoimmune disease. Identification of factors distinguishing the microbiota of healthy and diseased gut. [46]
Members of the Bacillota and Bacteroidota phyla make up a majority of the bacterial species in the human intestinal microbiota (the "gut microbiome"). The healthy human gut microbiome consists of 109 abundant species of which 31 (19.7%) are members of the Bacteroidetes while 63 (40%) and 32 (20%) belong to Bacillota and Actinomycetota. [26]
Co-occurrence networks show difference in gut microbiota between herbivorous and carnivorous cichlids Nodes coloured according to phylum. The herbivore network has higher complexity (156 nodes and 339 edges) compared to the carnivore network (21 nodes and 70 edges).
Diets in developed countries have lost microbiota-accessible carbohydrates which is the cause of a substantial depletion of gut microbiota taxa. This loss of microbiota diversity is likely involved in the increasing propensity for a broad range of inflammatory diseases, such as allergic disease, asthma, inflammatory bowel disease (IBD), obesity ...
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