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Natural killer T (NKT) cells are a heterogeneous group of T cells that share properties of both T cells and natural killer cells. Many of these cells recognize the non-polymorphic CD1d molecule, an antigen-presenting molecule that binds self and foreign lipids and glycolipids. They constitute only approximately 1% of all peripheral blood T ...
The neoplastic cells of this disease display a mature T-cell immunophenotype, with the majority of cases showing a CD4-/CD8+ T-cell subset immunophenotype versus other permutations of those markers. [8] [9] Variable expression of CD11b, CD56, and CD57 [10] are observed. Immunohistochemistry for perforin, TIA-1, and granzyme B are usually ...
Aggressive NK-cell leukemia is a disease with an aggressive, systemic proliferation of natural killer cells (NK cells) and a rapidly declining clinical course. [ 1 ] [ 2 ] [ 3 ] It is also called aggressive NK-cell lymphoma .
The T cells that may become infected by EBV are natural killer T cells (NK cells), Gamma delta T cells (γδ T cells), cytotoxic T cells (CTL), helper T cells (T h cells), and follicular B helper T cells (T FH cells). [13] The means by which EBV establishes a dendritic-histiocytic cell (i.e. follicular dendritic cell) infection are unclear ...
Anaplastic large cell lymphoma (ALCL) is a subtype of mature T-cell lymphoma involving T-cells or natural killer (NK) cells, representing 12% of patients. [9] It can be recognized by a constant expression of the tumour receptor necrosis factor CD30, a membrane protein expressed by activated T and B cells, in the cancer cells. [13]
Peripheral T-cell lymphoma (PTCL) is defined as a diverse group of aggressive lymphomas that develop from mature-stage white blood cells called T-cells and natural killer cells (see figure for an overview of PTCL subtypes). PTCL is a type of non-Hodgkin's lymphoma (NHL). [2] NHL affects two particular types of white blood cells: B-cells and T ...
T-cell lymphoma is a rare form of cancerous lymphoma affecting T-cells. [1] Lymphoma arises mainly from the uncontrolled proliferation of lymphocytes, such as T-cells, and can become cancerous. [2] T-cell lymphoma is categorized under Non-Hodgkin lymphoma (NHL) and represents less than 15% of all Non-Hodgkin's diseases in the category. [3]
CD8 + cytotoxic T cells (T c 1) T-Bet + interferon gamma producing group 1 ILCs(ILC1 and Natural killer cells) CD4 + T H 1 Cells. It has been found in both mice and humans that the signature cytokines for these cells are interferon gamma and lymphotoxin alpha.