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  2. Atypia - Wikipedia

    en.wikipedia.org/wiki/Atypia

    Marked atypia of type 2 pneumocytes is a characteristic finding in association with treatment with busulfan and other chemotherapeutic agents.. Atypia (from Greek, a + typos, without type; a condition of being irregular or nonstandard) [1] is a histopathologic term for a structural abnormality in a cell, i.e. it is used to describe atypical cells.

  3. Reactive lymphocyte - Wikipedia

    en.wikipedia.org/wiki/Reactive_lymphocyte

    The presence of Downey cells were observed in many COVID-19 cases, together with the atypical plasmacytoid lymphocytes (which could be one of the less usual atypical lymphocyte types). [ 9 ] [ 10 ] Some observations even suggest that the presence of particular reactive lymphocytes in some of the infected patients could be an indicator of a ...

  4. Nuclear atypia - Wikipedia

    en.wikipedia.org/wiki/Nuclear_atypia

    Nuclear atypia refers to abnormal appearance of cell nuclei. It is a term used in cytopathology and histopathology. Atypical nuclei are often pleomorphic. Nuclear atypia can be seen in reactive changes, pre-neoplastic changes and malignancy. Severe nuclear atypia is, in most cases, considered an indicator of malignancy.

  5. Koilocyte - Wikipedia

    en.wikipedia.org/wiki/Koilocyte

    ThinPrep pap smear with group of normal cervical cells on left and HPV-infected cells showing features typical of koilocytes: enlarged (x2 or x3) nuclei and hyperchromasia. A koilocyte is a squamous epithelial cell that has undergone a number of structural changes, which occur as a result of infection of the cell by human papillomavirus (HPV). [1]

  6. Pleomorphism (cytology) - Wikipedia

    en.wikipedia.org/wiki/Pleomorphism_(cytology)

    Despite the prevalence of pleomorphism in human pathology, its role in disease progression is unclear. In epithelial tissue, pleomorphism in cellular size can induce packing defects and disperse aberrant cells. [5] But the consequence of atypical cell and nuclear morphology in other tissues is unknown.

  7. Peripheral blood mononuclear cell - Wikipedia

    en.wikipedia.org/wiki/Peripheral_blood...

    A peripheral blood mononuclear cell (PBMC) is any peripheral blood cell having a round nucleus. [1] These cells consist of lymphocytes (T cells, B cells, NK cells) and monocytes, whereas erythrocytes and platelets have no nuclei, and granulocytes (neutrophils, basophils, and eosinophils) have multi-lobed nuclei. In humans, lymphocytes make up ...

  8. White blood cell differential - Wikipedia

    en.wikipedia.org/wiki/White_blood_cell_differential

    A white blood cell differential is a medical laboratory test that provides information about the types and amounts of white blood cells in a person's blood. The test, which is usually ordered as part of a complete blood count (CBC), measures the amounts of the five normal white blood cell types – neutrophils, lymphocytes, monocytes, eosinophils and basophils – as well as abnormal cell ...

  9. Anti-neutrophil cytoplasmic antibody - Wikipedia

    en.wikipedia.org/wiki/Anti-neutrophil_cytoplasm...

    Immunofluorescence (IF) on ethanol-fixed neutrophils is used to detect ANCA, although formalin-fixed neutrophils may be used to help differentiate ANCA patterns. ANCA can be divided into four patterns when visualised by IF; cytoplasmic ANCA (c-ANCA), C-ANCA (atypical), perinuclear ANCA (p-ANCA) and atypical ANCA (a-ANCA), also known as x-ANCA. c-ANCA shows cytoplasmic granular fluorescence ...