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The most common parameters measured in spirometry are vital capacity (VC), forced vital capacity (FVC), forced expiratory volume (FEV) at timed intervals of 0.5, 1.0 (FEV1), 2.0, and 3.0 seconds, forced expiratory flow 25–75% (FEF 25–75) and maximal voluntary ventilation (MVV), [10] also known as Maximum breathing capacity. [11]
Minute ventilation (or respiratory minute volume or minute volume) is the volume of gas inhaled (inhaled minute volume) or exhaled (exhaled minute volume) from a person's lungs per minute. It is an important parameter in respiratory medicine due to its relationship with blood carbon dioxide levels .
Tidal breathing is normal, resting breathing; the tidal volume is the volume of air that is inhaled or exhaled in only a single such breath. The average human respiratory rate is 30–60 breaths per minute at birth, [ 2 ] decreasing to 12–20 breaths per minute in adults.
Pulmonary function testing (PFT) is a complete evaluation of the respiratory system including patient history, physical examinations, and tests of pulmonary function. The primary purpose of pulmonary function testing is to identify the severity of pulmonary impairment. [1]
In 1960, the European Community for Coal and Steel (ECCS) first recommended guidelines for spirometry. [7] The organization then published predicted values for parameters such as spirometric indices, residual volume, total lung capacity, and functional residual capacity in 1971. [8]
Pulmonary compliance is calculated using the following equation, where ΔV is the change in volume, and ΔP is the change in pleural pressure: = For example, if a patient inhales 500 mL of air from a spirometer with an intrapleural pressure before inspiration of −5 cm H 2 O and −10 cm H 2 O at the end of inspiration.
A normal adult has a vital capacity between 3 and 5 litres. [3] A human's vital capacity depends on age, sex, height, mass, and possibly ethnicity. [ 4 ] However, the dependence on ethnicity is poorly understood or defined, as it was first established by studying black slaves in the 19th century [ 5 ] and may be the result of conflation with ...
Ideally, the oxygen provided via ventilation would be just enough to saturate the blood fully. In the typical adult, 1 litre of blood can hold about 200 mL of oxygen; 1 litre of dry air has about 210 mL of oxygen. Therefore, under these conditions, the ideal ventilation perfusion ratio would be about 0.95.