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Acinic cell carcinoma is a malignant tumor representing 2% of all salivary tumors. 90% of the time found in the parotid gland, 10% intraorally on buccal mucosa or palate. The disease presents as a slow growing mass, associated with pain or tenderness in 50% of the cases.
Relative incidence of parotid tumors, with Warthin's tumor near top right. [4] The gland most likely affected is the parotid gland. In fact, it is the only tumor virtually restricted to the parotid gland. Warthin's tumor is the second most common benign parotid tumor after pleomorphic adenoma, but its prevalence is steadily increasing. [5]
Carcinoma ex pleomorphic adenoma (ca ex PA) is a type of cancer typically found in the parotid gland. It arises from the benign tumour pleomorphic adenoma. Its prognosis depends on the stage. Early tumours have essentially a benign behaviour. [1]
Fast neutron therapy has been used successfully to treat salivary gland tumors, [14] and has shown to be significantly more effective than photons in studies treating unresectable salivary gland tumors. [15] [16] Chemotherapy Currently little is known about the efficacy of chemotherapy in treating salivary gland tumours. Chemotherapy, which ...
Pleomorphic adenoma (or benign mixed tumor) is a common benign salivary gland neoplasm characterised by neoplastic proliferation of epithelial (ductal) cells along with myoepithelial components, having a malignant potentiality. It is the most common type of salivary gland tumor and the most common tumor of the parotid gland.
Neoplastic lesions of the parotid salivary gland can either be benign or malignant. Within the parotid gland, nearly 80% of tumours are benign. [17] Benign lesions tend to be painless, asymptomatic and slow-growing. The most common salivary gland neoplasms in children are hemangiomas, lymphatic malformations, and pleomorphic adenomas. [13]
The exact cause of malignant parotid tumors is still unknown, however they can be caused by metastasis (spread of cancer) from other areas of the body, certain work exposures, reduced immunity, HIV, as well as radiation exposure. [5] Contrary to other cancers, it is believed that smoking and drinking do not influence salivary gland malignancies ...
Salivary duct carcinoma (SDC) is a rare type of aggressive cancer that arises from the salivary glands. [1] It is predominantly seen in men and, generally, has a poor prognosis. [2] Other high grade carcinomas can mimic SDC. About 40-60% of SDC arise in pleomorphic adenomas. [3] Most, if not all, SDCs express androgen receptor by ...
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