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Emphysema is a lower respiratory tract disease, [7] characterised by enlarged air-filled spaces in the lungs, that can vary in size and may be very large. The spaces are caused by the breakdown of the walls of the alveoli , which replace the spongy lung tissue .
Endobronchial valves may be the first successful medical device treatment of emphysema, a disease that affects millions of people worldwide and has no known cure, being managed traditionally by lung transplantation and/or lung volume reduction surgery (though some people do not meet the eligibility requirements for one or both of these invasive ...
BLVR was initially developed in the early 2000s [1] [2] as a minimally invasive treatment for severe COPD that is primarily caused by emphysema. BLVR evolved from earlier surgical approaches first developed in the 1950s [3] to reduce lung volume by removing damaged portions of the lungs via pneumonectomy or wedge resection.
The most common cause of emphysema is smoking and smoking cessation is mandatory if this incurable disease is to be treated. Prevention of bronchoconstriction by this pathway is vital for people with emphysema and there are several anticholinergic medications that in combination with mucous thinning agents such as Guaifenesin cause significant ...
Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. [8] GOLD 2024 defined COPD as a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea or shortness of breath, cough, sputum production or exacerbations) due to abnormalities of the airways (bronchitis ...
Other causes can include acid reflux, asthma, allergies, or other chronic medical conditions, adds Richard Watkins, M.D., an infectious disease physician and professor of medicine at the Northeast ...
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