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While the cause of rheumatoid arthritis is not clear, it is believed to involve a combination of genetic and environmental factors. [1] The underlying mechanism involves the body's immune system attacking the joints. [1] This results in inflammation and thickening of the joint capsule. [1] It also affects the underlying bone and cartilage. [1]
Rheumatoid arthritis (RA) is a disorder in which the body's own immune system starts to attack body tissues. [72] The attack is not only directed at the joint but to many other parts of the body. In rheumatoid arthritis, most damage occurs to the joint lining and cartilage which eventually results in erosion of two opposing bones.
Juvenile, in this context, refers to disease onset before 16 years of age, while idiopathic refers to a condition with no defined cause, and arthritis is inflammation within the joint. [4] JIA is an autoimmune, noninfective, inflammatory joint disease, the cause of which remains poorly understood. It is characterised by chronic joint inflammation.
Women with physical disabilities are at a greater risk of having lower bone mass and are at risk for osteoporosis. [54] Women with ID and Down syndrome often go through menopause at an earlier age than other women. [55] Women with various disabilities sometimes show different symptoms from decreased estrogen levels during menopause. [23]
Globally, about 3 million children and young adults are impacted by this disease. [37] In the US it affects about 250,000-294,000 children making it one of the most common groups of childhood diseases. [12] However, due to not having consistent guidelines or criteria for diagnosis, this number is an estimation based on smaller population groups ...
Between 2001 and 2022, suicide rates actually increased significantly for men and women over 55, while it declined for those age 15 to 34. Making sense of the statistics
Children with these conditions may have the same diagnoses, but their abilities and levels of functioning widely vary across and within individuals over time. The first draft of the International Classification of Functioning, Disability and Health for Children and Youth (ICF-CY) was completed in year 2003 and published in 2007. The ICF-CY was ...
Over 45 for men and over 55 for women. Family history. Having a family history of early heart disease. Sex. People born male are at increased risk. Congenital defects. Having problems with your ...