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  2. Haldane's dilemma - Wikipedia

    en.wikipedia.org/wiki/Haldane's_dilemma

    Note that Haldane's model assumes independence of genes at different loci; if the selection intensity is 0.1 for each gene moving towards fixation, and there are N such genes, then the reproductive capacity of the species will be lowered to 0.9 N times the original capacity. Therefore, if it is necessary for the population to fix more than one ...

  3. J. B. S. Haldane - Wikipedia

    en.wikipedia.org/wiki/J._B._S._Haldane

    Haldane's article on abiogenesis in 1929 introduced the "primordial soup theory", which became the foundation for the concept of the chemical origin of life. He established human gene maps for haemophilia and colour blindness on the X chromosome, and codified Haldane's rule on sterility in the heterogametic sex of hybrids in species.

  4. Haldane's rule - Wikipedia

    en.wikipedia.org/wiki/Haldane's_rule

    In humans, barring intersex conditions causing aneuploidy and other unusual states, it is the male that is heterogametic, with XY sex chromosomes.. Haldane's rule is an observation about the early stage of speciation, formulated in 1922 by the British evolutionary biologist J. B. S. Haldane, that states that if — in a species hybrid — only one sex is inviable or sterile, that sex is more ...

  5. Category:Works by J. B. S. Haldane - Wikipedia

    en.wikipedia.org/wiki/Category:Works_by_J._B._S...

    Pages in category "Works by J. B. S. Haldane" The following 6 pages are in this category, out of 6 total. ... Haldane's dilemma; Haldane's rule; O. On Being the Right ...

  6. Neutral theory of molecular evolution - Wikipedia

    en.wikipedia.org/wiki/Neutral_theory_of...

    Haldane's dilemma regarding the cost of selection was used as motivation by Kimura. Haldane estimated that it takes about 300 generations for a beneficial mutation to become fixed in a mammalian lineage, meaning that the number of substitutions (1.5 per year) in the evolution between humans and chimpanzees was too high to be explained by ...

  7. Group selection - Wikipedia

    en.wikipedia.org/wiki/Group_selection

    R.A. Fisher in 1930 [17] and J.B.S. Haldane in 1932 [18] set out the mathematics of kin selection, with Haldane famously joking that he would willingly die for two brothers or eight cousins. [19] In this model, genetically related individuals cooperate because survival advantages to one individual also benefit kin who share some fraction of the ...

  8. Objections to evolution - Wikipedia

    en.wikipedia.org/wiki/Objections_to_evolution

    Objections to evolution have been raised since evolutionary ideas came to prominence in the 19th century. When Charles Darwin published his 1859 book On the Origin of Species, his theory of evolution (the idea that species arose through descent with modification from a single common ancestor in a process driven by natural selection) initially met opposition from scientists with different ...

  9. Substrate inhibition in bioreactors - Wikipedia

    en.wikipedia.org/wiki/Substrate_inhibition_in...

    The most common solution is to change the growth from a batch process to a fed-batch process. Other methods to overcome substrate inhibition include the addition of another substrate type in order to develop alternative metabolic pathways , immobilizing the cells or increasing the biomass concentration.