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The Radial Unit Hypothesis (RUH) is a conceptual theory of cerebral cortex development, first described by Pasko Rakic. It states that the cerebral cortex develops during embryogenesis as an array of interacting cortical columns , or 'radial units', each of which originates from a transient stem cell layer called the ventricular zone , which ...
The ventricular and subventricular zones exist inferior to the intermediate zone and communicate with other zones through cell signalling. These zones additionally create neurons destined to migrate to other areas in the cortex. [1] [6] The marginal zone, along with the cortical zone, make up the 6 layers that form the cortex. This zone is the ...
The marginal zone is the region at the interface between the non-lymphoid red pulp and the lymphoid white-pulp of the spleen. (Some sources consider it to be the part of red pulp which borders on the white pulp, while other sources consider it to be neither red pulp nor white pulp.) A marginal zone also exists in lymph nodes. [1] [2]
Flannery's hypothesis was meant to help explain the adoption of agriculture in the Neolithic Revolution.Unpersuaded by "the facile explanation of prehistoric environmental change" [2] Flannery suggested (following Lewis Binford's equilibrium model) that population growth in optimal habitats led to demographic pressure within nearby marginal habitats as daughter groups migrated.
Cajal–Retzius cells were described to migrate tangentially in the marginal zone, a superficial layer of the preplate in the cortical neuroepithelium, [3] [4] According to some studies, this migration depends on the site where the cell was generated, showing a link between the origin, the migration and the destination of the cell. [5]
Additionally, after 75 days of formation, cerebral organoids show a rudimentary marginal zone, a cell-poor region. The formation of layered cortical plate is very basic in cerebral organoids and suggests the organoid lacks the cues and factors to induce formation of layer II-VI organization. [1]
As The Post’s map shows, the cost of entering the congestion zone, defined as entering Manhattan anywhere on 60th Street or below, in a car from Jan. 5 will be significantly higher —between $9 ...
Reelin-expressing cells in the prenatal and early postnatal brain are predominantly found in the marginal zone (MZ) of the cortex and in the temporary subpial granular layer (SGL), which is manifested to the highest extent in human, [31] and in the hippocampal stratum lacunosum-moleculare and the upper marginal layer of the dentate gyrus.