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Permethrin is a medication and an insecticide. [6] [7] As a medication, it is used to treat scabies and lice. [8] It is applied to the skin as a cream or lotion. [6] As an insecticide, it can be sprayed onto outer clothing or mosquito nets to kill the insects that touch them. [7] [9] Side effects include rash and irritation where it is applied. [8]
At first, treatment is usually with topical permethrin 1% cream, which can be bought over the counter without a prescription. It is applied to the areas affected by pubic lice and washed off after 10 minutes. [6] Brands of permethrin include 'Lyclear', available in the UK as a creme rinse or dermal cream at 5% strengths.
Resistance of head lice to insecticides such as lindane, malathion, phenothrin and permethrin has been reported. [ 9 ] [ 10 ] [ 11 ] A 2021 systematic review and meta-analysis found that the mean frequency of pyrethroid resistance of lice was 77% globally, and even 100% in several countries (Australia, England, Israel, and Turkey). [ 12 ]
Pyrethroids such as permethrin have been commonly used; however, they have become less effective due to increasing pesticide resistance. [7] There is little evidence for alternative medicines. [9] Head-lice infestations are common, especially in children. [5] In Europe, they infect between 1 and 20% of different groups of people. [6]
Permethrin is a pyrethroid, meaning it is similar in structure to pyrethrin, but pyrethrin is not a precursor in the production of permethrin. ChemNerd ( talk ) 21:58, 31 January 2018 (UTC) [ reply ]
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Cream. A cream is a preparation usually for application to the skin.Creams for application to mucous membranes such as those of the rectum or vagina are also used. Creams may be considered pharmaceutical products, since even cosmetic creams are manufactured using techniques developed by pharmacy and unmedicated creams are highly used in a variety of skin conditions (dermatoses).
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