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Nephrotoxicity is toxicity in the kidneys.It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [1] There are various forms, [2] and some drugs may affect kidney function in more than one way.
A small proportion of individuals with analgesic nephropathy may develop end-stage kidney disease. Analgesic nephropathy was once a common cause of kidney injury and end-stage kidney disease in parts of Europe, Australia, and the United States. In most areas, its incidence has declined sharply since the use of phenacetin fell in the 1970s and ...
It is typically caused by kidney failure or is treatment-induced such as from antacids or supplements that contain magnesium. [1] [6] Less common causes include tumor lysis syndrome, seizures, and prolonged ischemia. [2] Diagnosis is based on a blood level of magnesium greater than 1.1 mmol/L (2.6 mg/dL).
Most people know that GLP-1 receptor agonist medications like Ozempic and Wegovy can cause relatively minor side effects like nausea and diarrhea. But new research confirms that more serious ...
In fact, calcium-containing antacids are known to cause changes in stool color. ... long-term use of acetaminophen can cause liver damage, especially if combined with alcohol. ...
Milk-alkali syndrome is an illness that is characterized by hypercalcaemia, kidney damage, and metabolic alkalosis. [17] This syndrome was discovered in the early 1900s when people began experiencing adverse effects from Bertrand Sippy's gastric ulcer treatment consisting of milk and alkali.
"People with advanced kidney disease or kidney stones may also need to be careful with eating large amounts of kale due to its oxalate and potassium content," cautions Newberry. "And many drugs ...
Some antacids also inhibit pepsin, an enzyme that can damage the esophagus in acid reflux. [2] [13] Antacids do not directly inhibit acid secretion, and thus are distinct from acid-reducing drugs like H 2-receptor antagonists or proton pump inhibitors. [4] Antacids do not kill the bacteria Helicobacter pylori, which causes most ulcers. [4]