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  2. List of benzodiazepines - Wikipedia

    en.wikipedia.org/wiki/List_of_benzodiazepines

    The tables below contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, along with their trade names and primary uses.

  3. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...

  4. Benzodiazepine - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine

    A benzodiazepine can be placed into one of three groups by its elimination half-life, or time it takes for the body to eliminate half of the dose. [189] Some benzodiazepines have long-acting active metabolites , such as diazepam and chlordiazepoxide, which are metabolised into desmethyldiazepam .

  5. Flurazepam - Wikipedia

    en.wikipedia.org/wiki/Flurazepam

    Flurazepam is a "classical" benzodiazepine; some other classical benzodiazepines include diazepam, clonazepam, oxazepam, lorazepam, nitrazepam, bromazepam, and clorazepate. [16] Flurazepam generates an active metabolite, N-desalkylflurazepam, with a very long elimination half-life. [3]

  6. Triazolam - Wikipedia

    en.wikipedia.org/wiki/Triazolam

    Triazolam, like other benzodiazepines, is susceptible to misuse and abuse. Its rapid onset of action and short half life contribute to its abuse potential, but its relative obscurity compared to other fast-acting benzodiazepines (such as alprazolam or lorazepam) prevent its abuse from becoming particularly commonplace. Likewise, because it is ...

  7. Temazepam - Wikipedia

    en.wikipedia.org/wiki/Temazepam

    The unchanged drug was 96% bound to plasma proteins. The blood-level decline of the parent drug was biphasic, with the short half-life ranging from 0.4 to 0.6 hours and the terminal half-life from 3.5 to 18.4 hours (mean 8.8 hours), depending on the study population and method of determination. [62]

  8. Flutazolam - Wikipedia

    en.wikipedia.org/wiki/Flutazolam

    While flutazolam has a very short half-life of only 3.5 hours, n-desalkylflurazepam has a long half-life of between 47–100 hours. [4] Flutazolam is closely related in structure to another benzodiazepine, haloxazolam. [5] [6]

  9. Etizolam - Wikipedia

    en.wikipedia.org/wiki/Etizolam

    It has a mean elimination half life of about 3.4 hours. [4] [2] [3] Etizolam possesses potent hypnotic properties, [23] and is comparable with other short-acting benzodiazepines. [4] Etizolam acts as a positive allosteric modulator of the GABA A receptor by agonizing the receptor's benzodiazepine site. [24]