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Hyperuricosuria is a medical term referring to the presence of excessive amounts of uric acid in the urine. For men this is at a rate greater than 800 mg/day, and for women, 750 mg/day. [1] Notable direct causes of hyperuricosuria are dissolution of uric acid crystals in the kidneys or urinary bladder, and hyperuricemia.
Uric acid displays lactam–lactim tautomerism. [4] Uric acid crystallizes in the lactam form, [5] with computational chemistry also indicating that tautomer to be the most stable. [6] Uric acid is a diprotic acid with pK a1 = 5.4 and pK a2 = 10.3. [7] At physiological pH, urate predominates in solution. [medical citation needed]
VLCDs can achieve higher short-term weight loss compared to other more modest or gradual calorie restricted diets, and the maintained long-term weight loss is similar or greater. [10] [21] [22] VLCDs were shown to reduce lean body mass. [23] [24] Combining VLCD with other obesity therapies yield more effective results in weight loss. [25]
Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [5] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...
The phosphate reacts with the acid, and the calcium is excreted by the kidneys. [41] Hypocitraturia: the urine has an abnormally low concentration of citrate, which normally helps to dissolve free calcium. [41] The urine has a low pH, which stops uric acid from dissolving, leading to crystals that act as a nidus for calcium stone formation. [41]
The Autoimmune Protocol (AIP) diet is an elimination diet designed to help reduce inflammation, manage symptoms and improve quality of life for people with autoimmune diseases.
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