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Lysogenic Cycle [9] An example of a virus that uses the lysogenic cycle to its advantage is the Herpes Simplex Virus. [10] After first entering the lytic cycle and infecting a human host, it enters the lysogenic cycle. This allows it to travel to the nervous system's sensory neurons and remain undetected for long periods of time.
A lysogen or lysogenic bacteria is a bacterial cell that can produce and transfer the ability to produce a phage. [1] A prophage is either integrated into the host bacteria 's chromosome or more rarely exists as a stable plasmid within the host cell.
The lytic pathway causes the host to produce and release progeny virions, usually killing it in the process. The lysogenic pathway involves the virus inserting itself into the bacterium's chromosome. At a later stage, the viral genome is activated, and it continues along the lytic pathway of producing and releasing progeny virions.
Integration of prophages into the bacterial host is the characteristic step of the lysogenic cycle of temperate phages. Prophages remain latent in the genome through multiple cell divisions until activation by an external factor, such as UV light, leading to production of new phage particles that will lyse the cell and spread.
The life cycle of lambda phages is controlled by cI and Cro proteins. The lambda phage will remain in the lysogenic state if cI proteins predominate, but will be transformed into the lytic cycle if cro proteins predominate. The cI dimer may bind to any of three operators, O R 1, O R 2, and O R 3, in the order O R 1 > O R 2 > O R 3.
Viruses may undergo two types of life cycles: the lytic cycle and the lysogenic cycle. In the lytic cycle, the virus introduces its genome into a host cell and initiates replication by hijacking the host's cellular machinery to make new copies of the virus. [12] In the lysogenic life cycle, the viral genome is incorporated into the host genome.
Virus latency (or viral latency) is the ability of a pathogenic virus to lie dormant within a cell, denoted as the lysogenic part of the viral life cycle. [1] A latent viral infection is a type of persistent viral infection which is distinguished from a chronic viral infection. Latency is the phase in certain viruses' life cycles in which ...
The lysogenic cycle, however, is when the viral DNA is incorporated into the host genome, allowing it to go unnoticed by the immune system. Eventually, it gets reactivated and enters the lytic cycle, giving it an indefinite "shelf life" so to speak.