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  2. Etoposide - Wikipedia

    en.wikipedia.org/wiki/Etoposide

    Etoposide, sold under the brand name Vepesid among others, is a chemotherapy medication used for the treatments of a number of types of cancer including testicular cancer, lung cancer, lymphoma, leukemia, neuroblastoma, and ovarian cancer. [2] It is also used for hemophagocytic lymphohistiocytosis. [3] It is used by mouth or injection into a ...

  3. Epipodophyllotoxin - Wikipedia

    en.wikipedia.org/wiki/Epipodophyllotoxin

    Etoposide, an epipodophyllotoxin. Epipodophyllotoxins are substances naturally occurring in the root of American Mayapple plant (Podophyllum peltatum). Some epipodophyllotoxin derivatives are currently used in the treatment of cancer. These include etoposide and teniposide. They act as anti-cancer drugs by inhibiting topoisomerase II. [1]

  4. Topoisomerase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Topoisomerase_inhibitor

    Etoposide is a highly schedule-dependent drug and is typically administered orally and recommended to take twice the dosage for effective treatment. [ 13 ] [ 68 ] However, with the selective dosage, etoposide treatment is dose limiting proposing toxic effects like myelosupression (leukopenia) and primarily hematologic.

  5. Podophyllotoxin - Wikipedia

    en.wikipedia.org/wiki/Podophyllotoxin

    Podophyllotoxin derived antitumor agents include etoposide and teniposide. [10] [37] These drugs have been successfully used in therapy against numerous cancers including testicular, breast, pancreatic, lung, stomach, and ovarian cancers. [32] Derivatives of podophyllotoxin that have been engineered for their ability to fight tumors. [38]

  6. EPOCH (chemotherapy) - Wikipedia

    en.wikipedia.org/wiki/EPOCH_(chemotherapy)

    Etoposide: a topoisomerase inhibitor from the group of epipodophyllotoxins; Prednisolone : a glucocorticoid hormone that can cause apoptosis and lysis of both normal and malignant lymphocytes ; Oncovin , also known as vincristine : a vinca alkaloid that binds to the protein tubulin , thereby preventing the formation of microtubules and mitosis ;

  7. Hagerty: The public doesn't care who does Hegseth's ... - AOL

    www.aol.com/news/hagerty-public-doesnt-care-fbi...

    Sen. Bill Hagerty, R-Tenn., a prominent ally of Donald Trump, said voters don't care who conducts background checks into the president-elect's Cabinet picks and that Trump would fire members of ...

  8. Drug withdrawal - Wikipedia

    en.wikipedia.org/wiki/Drug_withdrawal

    Drug withdrawal, drug withdrawal syndrome, or substance withdrawal syndrome [1] is the group of symptoms that occur upon the abrupt discontinuation or decrease in the intake of pharmaceutical or recreational drugs. In order for the symptoms of withdrawal to occur, one must have first developed a form of drug dependence.

  9. Jelly Roll Says He Was a '550-Lb. Zombie' Before Dramatic ...

    www.aol.com/lifestyle/jelly-roll-says-550-lb...

    Jelly Roll says his fear of acid reflux prevented him from trying weight loss drugs like Ozempic — and that he has lost about 140 lbs. naturally ... “I started realizing that the same patterns ...