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  2. Temsirolimus - Wikipedia

    en.wikipedia.org/wiki/Temsirolimus

    Temsirolimus, sold under the brand name Torisel, is an intravenous drug for the treatment of renal cell carcinoma (RCC), developed by Wyeth Pharmaceuticals and approved by the U.S. Food and Drug Administration (FDA) in May 2007, [3] and was also approved by the European Medicines Agency (EMA) in November 2007. [1]

  3. Drug Fails: At Least It's Approved Already - AOL

    www.aol.com/news/2012-05-16-drug-fails-at-least...

    Usually cancer drugs go after patients with no other options first before moving on to a first-line indication, so it's curious that Pfizer's (NYS: PFE) Torisel, which is approved as a first-line ...

  4. Kidney Cancer? There's a Drug for That - AOL

    www.aol.com/news/2012-01-31-kidney-cancer-theres...

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  5. New hope for kidney cancer treatment using existing drugs - AOL

    www.aol.com/hope-kidney-cancer-treatment-using...

    New hope for kidney cancer treatment using existing drugs. Nina Massey, PA Science Correspondent. November 23, 2022 at 11:00 AM.

  6. Kidney cancer - Wikipedia

    en.wikipedia.org/wiki/Kidney_cancer

    In Europe, kidney cancer accounts for nearly 3% of all cancer cases. [70] Kidney cancer is the eighth most common cancer in the UK (around 10,100 people were diagnosed with the disease in 2011), and it is the fourteenth most common cause of cancer death (around 4,300 people died in 2012). [71]

  7. mTOR inhibitors - Wikipedia

    en.wikipedia.org/wiki/MTOR_inhibitors

    mTOR inhibitors are a class of drugs used to treat several human diseases, including cancer, autoimmune diseases, and neurodegeneration. They function by inhibiting the mammalian target of rapamycin (mTOR) (also known as the mechanistic target of rapamycin), which is a serine/threonine-specific protein kinase that belongs to the family of phosphatidylinositol-3 kinase (PI3K) related kinases ...

  8. Combo to Beat the Competition? - AOL

    www.aol.com/news/2012-08-13-combo-to-beat-the...

    No doubt, the kidney cancer market is quite crowded. Pfizer (NYS: PFE) alone has three drugs approved to treat the disease. And then there's Bayer and Onyx Pharmaceuticals' (NAS: ONXX) Nexavar ...

  9. Sunitinib - Wikipedia

    en.wikipedia.org/wiki/Sunitinib

    Sunitinib is approved for the treatment of metastatic renal cell carcinoma. Other therapeutic options in this setting are pazopanib (Votrient), sorafenib (Nexavar), temsirolimus (Torisel), interleukin-2 (Proleukin), everolimus (Afinitor), bevacizumab (Avastin), and aldesleukin. Renal cell carcinoma is generally resistant to chemotherapy or ...

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