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Sjögren's syndrome was originally proposed as a specific, self-perpetuating, immune system-mediated loss of exocrine glands, specifically acinar and ductal cells. Although this explains the more obvious symptoms (such as the lack of saliva and lacrimal fluid ), it does not explain the more widespread systemic effects seen in the progression of ...
The lacrimal gland is a compound tubuloacinar gland, it is made up of many lobules separated by connective tissue, each lobule contains many acini.The acini composed of large serous cells which, produce a watery serous secretion, serous cells are filled with lightly stained secretory granules and surrounded by well-developed myoepithelial cells and a sparse, vascular stroma.
Historically, bilateral parotid and lacrimal gland enlargement was characterized by the term Mikulicz's disease if the enlargement appeared apart from other diseases. If it was secondary to another disease, such as tuberculosis, sarcoidosis, lymphoma, and Sjögren's syndrome, the term used was Mikulicz's syndrome.
Keratoconjunctivitis sicca can be caused by inadequate tear production from lacrimal hyposecretion. [13] [14] The aqueous tear layer is affected, resulting in aqueous tear deficiency (ATD). [14] The lacrimal gland does not produce sufficient tears to keep the entire conjunctiva and cornea covered by a complete layer. [13]
Idiopathic orbital inflammation has a varied clinical presentation depending on the involved tissue. It can range from a diffuse inflammatory process to a more localized inflammation of muscle, lacrimal gland or orbital fat. [7] Its former name, orbital pseudotumor, is derived due to resemblance to a neoplasm.
Primary salivary gland EMZL (also termed MALT lymphoma of the salivary glands) or, in cases primarily involving the lacrimal glands, primary lacrimal gland EMZL (also termed MALT lymphoma of the lacrimal gland) is a complication of Sjögren syndrome, an autoimmune disease characterized by chronic inflammation of the salivary and/or lacrimal ...
This procedure is indicated when there is recurrent swelling and pain on the face but ultrasound has not revealed any problems. If Sjögren syndrome (also known as Sicca syndrome, an autoimmune disease that affects the lacrimal and salivary glands, causing reduced tears and saliva production) is suspected, this procedure is useful.
Sometimes, especially in women, stones may develop in the lacrimal gland, causing recurrent bouts of dacryocystitis; this condition is called "acute dacryocystic retention syndrome." [5] Also due to pneumococcus, infection due to surrounding structure such as paranasal sinuses. lacrimal sac may extrude pus through the punctum.