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Prospects for tuberculosis control and elimination in a hypothetical high-burden country, starting in 2015. Tuberculosis has been a curable illness since the 1940s when the first drugs became available, although multidrug-resistant and extensively drug-resistant TB present an increasing challenge. [5]
The total number of tuberculosis cases has been decreasing since 2005, while new cases have decreased since 2002. [ 78 ] Tuberculosis [ clarification needed ] incidence is seasonal, with peaks occurring every spring and summer.
NCDs are primarily associated with socio-economic status and comprise 7 out of 10 leading causes of death, 85% of those occurring in low- and middle-income countries, according to the World Health ...
Resistant strains of M. tuberculosis have developed resistance to more than one TB drug, due to mutations in their genes. In addition, pre-existing first-line TB drugs such as rifampicin and streptomycin have decreased efficiency in clearing intracellular M. tuberculosis due to their inability to effectively penetrate the macrophage niche. [31]
Health chiefs have issued a warning after cases of tuberculosis in the UK rose in 2023, with more people seeking medical treatment for the serious lung infection which can leave patients coughing ...
China has the world's third largest cases of tuberculosis (after India and Indonesia), but progress in tuberculosis control was slow during the 1990s. Detection of tuberculosis had stagnated at around 30% of the estimated total of new cases, and multidrug-resistant tuberculosis [ 1 ] was a major problem.
A large number of people who survived tuberculosis still experience symptoms such as breathlessness and coughing. Although the severity is not well understood, some people have reduced quality of life and exercise capacity. [4] [2] In severe cases, people may experience hospitalizations and death related to respiratory causes. [2]
(Worth noting: The U.S. does not currently vaccinate against tuberculosis, given the low risk of exposure.) About 95% of people need to be vaccinated against measles to prevent it from reemerging.