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The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts.
The same Hox protein can act as a repressor at one gene and an activator at another. The ability of Hox proteins to bind DNA is conferred by a part of the protein referred to as the homeodomain. The homeodomain is a 60-amino-acid-long DNA-binding domain (encoded by its corresponding 180-base-pair DNA sequence, the homeobox
Homeobox genes encode homeodomain protein products that are transcription factors sharing a characteristic protein fold structure that binds DNA to regulate expression of target genes. [ 3 ] [ 4 ] [ 2 ] Homeodomain proteins regulate gene expression and cell differentiation during early embryonic development, thus mutations in homeobox genes can ...
Only 1 percent of funding for health-care research and innovation went to women’s health issues in 2020, per a McKinsey & Company report. Plus, humans have a very unique biology, so good models ...
Homeobox protein Hox-C6 is a protein that in humans is encoded by the HOXC6 gene. [ 5 ] [ 6 ] [ 7 ] Hox-C6 expression is highest in the fallopian tube and ovary. [ 8 ] HoxC6 has been highly expressed in many types of cancers including prostate, breast, and esophageal squamous cell cancer.
ShutterstockIt's no secret that protein is an essential nutrient for building muscle mass, supporting healthy weight management, and bolstering the immune system. But protein isn't vital only for ...
Serving size: 3 ounces (85 grams) Calories: 84 Protein: 20 grams Fat: 0 grams Shrimp is a low-fat protein source rich in omega-3 fatty acids and selenium, which are crucial for heart health and ...
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