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Ligand-gated ion channels (LICs, LGIC), also commonly referred to as ionotropic receptors, are a group of transmembrane ion-channel proteins which open to allow ions such as Na +, K +, Ca 2+, and/or Cl − to pass through the membrane in response to the binding of a chemical messenger (i.e. a ligand), such as a neurotransmitter.
Examples of such channels include the cation-permeable nicotinic acetylcholine receptors, ionotropic glutamate-gated receptors, acid-sensing ion channels (ASICs), [16] ATP-gated P2X receptors, and the anion-permeable γ-aminobutyric acid-gated GABA A receptor. Ion channels activated by second messengers may also be categorized in this group ...
Cyclic nucleotide gated channel beta 3; Cyclic nucleotide-gated channel alpha 1; Cyclic nucleotide-gated channel alpha 2; Cyclic nucleotide-gated channel alpha 3; Cyclic nucleotide-gated channel alpha 4; Cyclic nucleotide–gated ion channel; Cys-loop receptor
Transient receptor potential channels (TRP channels) are a group of ion channels located mostly on the plasma membrane of numerous animal cell types. Most of these are grouped into two broad groups: Group 1 includes TRPC ( "C" for canonical), TRPV ("V" for vanilloid), TRPVL ("VL" for vanilloid-like), TRPM ("M" for melastatin), TRPS ("S" for soromelastatin), TRPN ("N" for mechanoreceptor ...
Pages in category "Ionotropic receptors" The following 7 pages are in this category, out of 7 total. ... Ligand-gated ion channel; P. P2X purinoreceptor
Receptor proteins can be classified by their location. Cell surface receptors, also known as transmembrane receptors, include ligand-gated ion channels, G protein-coupled receptors, and enzyme-linked hormone receptors. [1] Intracellular receptors are those found inside the cell, and include cytoplasmic receptors and nuclear receptors. [1]
This opens the ion channel, allowing extracellular ions into the cell. Ion permeability of the plasma membrane is altered, and this transforms the extracellular chemical signal into an intracellular electric signal which alters the cell excitability. [12] The acetylcholine receptor is a receptor linked to a cation channel. The protein consists ...
Nicotinic receptors cause the release of catecholamine from the adrenal medulla, and also site specific excitation or inhibition in brain. Both Nm and Nn receptor types are non-selective cation channels, permeable to sodium and potassium ions, in addition to that, Nn type receptors allow for calcium ion flow.